EFFECT OF DIFFERENT DISINTEGRANTS ON CIPROFLOXACIN CONVENTIONAL TABLETS
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 3
Abstract
The objective of the present study is to design and evaluate the effect of disintegrating agents such as Starch, Cross Caramellose Sodium and Sodium starch glycolate on ciprofloxacin tablet. The nature of the Ciprofloxacin which is slightly soluble in water which affects the drug disintegration process there by inhibits the drug release from the Conventional Tablet. Hence in the present study the effect of disintegrating agents at different concentrations is carried out on the ciprofloxacin hcl to find out the optimized concentration followed by stability studies for a period of 3 months.
Authors and Affiliations
Harish. G Ch. Bhargavi A. Riyajune Md. Yasmeen Syed Mohammed Ch. Murali Krishna Sk. Jilani Nirajana. V. A
Keywords
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