Effect of Drotaverine on cervical dilatation – A comparative study with Valethamate bromide.
Journal Title: IJSR-International Journal Of Scientific Research - Year 2016, Vol 5, Issue 12
Abstract
Objectives To compare the efficacy and safety of Drotaverine hydrochloride and Valethamate bromide in shortening of 1st stage of labour. Study design e prospective study was conducted at ALLURI SITARAMA RAJU ACADEMY OF MEDICAL SCIENCES, ELURU between August 2013 to October 2015. 300 patients in labor ( spontaneous or induced ) were selected. ey were equally divided into three groups. In group 1, an injection of Valethamate bromide 8 mg intramuscularly every half an hour for three doses. Group 2 consisted of 100 women who were administered one injection of Drotaverine hydrochloride 40 mg intramuscularly and repeated 2 hourly for maximum of three injections. Group 3 (n=100) acted as Control and were not given any drug. Comparative analysis was carried out regards to duration of early active phase of labour, rate of cervical dilatation, injection to delivery interval, mode of delivery, maternal outcome. t - test and chi - square test was used as statistical test of significance. Result 1. e average injection to delivery interval in Drotaverine is 192.26±75.155 minutes and in Valethamate is 262.72±134.5 minutes. e injection to end of first stage is 168.89±69.57 minutes in Drotaverine and 241.46±130.27 minutes in Valethamate. 2 e rate of cervical dilatation in Primigravida was 1.974 ±1.95 cm/hr in Valethamate , 2.188±0.63 cm/hr in Drotaverine and 1.163±0.45 cm/hr in Control group. In Multigravidae the values were 1.739±0.96 cm/hr in Valethamate, 2.496±1.23 cm/hr in Drotaverine and 1.482±0.58 cm/hr in Control group. Conclusion : In conclusion, as per the present study, it is found that the Drotaverine is superior to Valethamate as it reduces the duration of labor more effectively with very less adverse effects on mother and fetus compared to Valethamate and contol groups. When compared to Valethamate, Drotaverine is cost effective. Hence, Drotaverine can be recommended for shortening the duration of labor by hastening the cervical dilatation.
Authors and Affiliations
Dr. Vijaya Lakshmi K, Dr. Pavani Jannu, Dr. B. Naveena
Keywords
Related Articles
- EP ID EP349405
- DOI -
- Views 40
- Downloads 0
APPRAISAL OF THE RADIATION SAFETY PRACTICES IN JAMMU AMONG RADIOGRAPHERS IN JAMMU.
Aim: The aim of the study was to assess the knowledge and implementation of the radiation protection practices among radiographers in Jammu Materials and Methods: The study was a prospective cross sectional survey. Conve...
SERUM INFLAMMATORY MARKERS OF DIABETIC KIDNEY DISEASE AND THEIR CORRELATION TO LIPID PARAMETERS AMONG DIABETIC INDIVIDUALS OF EASTERN INDIA
Background : Diabetes mellitus is the leading cause of chronic renal failure . As the period of diabetes progresses there is simultaneous increase of inflammatory markers like high sensitive C reactive protein (hsCRP) wi...
Post-Operative Radiotherapy to Cancer Breast: is Dose to Contra Lateral Breast is Significant?
Breast cancer is the most common malignancy in women worldwide. With improving survival figures and early breast cancer detection, treatment related long term adverse effects of radiotherapy have become a concern. Contra...
EARLY RELEASE AND SPLIT THICKNESS SKIN GRAFTING OF UPPER EYELID BURNS TO PREVENT EYELID ECTROPION
Upper Eye lid burns are more common among the eye injuries. Adequate acute management of eyelid burns is necessary to prevent ectropion .Ectropion of the upper eyelid is usually associated with constant danger of kerato...
Fusion of Manubriosternal Joint: Role in Estimation of Age
Estimation of age of an individual from skeletal remains is a crucial step. Present work is an effort to study the sternum for estimation of age based on fusion of the manubriosternal joint. The sterna were obtained from...