Effect of four local anesthetics (tetracaine, bupivacaine, lidocaine and proparacaine) on intraocular pressure in rabbits- Comparison of an applanation and a rebound tonometer

Journal Title: Iranian Journal of Veterinary Science and Technology (IJVST) - Year 2020, Vol 12, Issue 1

Abstract

The type of device used, the type of local anesthetic agents, and the animal species may affect the intraocular pressure(IOP). Therefore, in order to determine these issues, the effects of four local anesthetics were investigated in 10 adult rabbits by ICare TA01i and Tono-Pen Vet tonometers. In the right eye of half of the rabbits and in the left eye of the other half of the rabbits, one drop of tetracaine was instilled. The IOP in each rabbit was measured using two tonometers, ICare and Tono-Pen Vet, before and each 5 minutes until 40 minutes later. The effects of other drugs were also studied at least with one-week interval. Based on the results of ICare tonometer, tetracaine significantly reduced the IOP immediately and 25 minutes after instillation. IOP changes after instillation of bupivacaine, lidocaine and proparacaine were not significant at any time compared to baseline values (p > 0.05). Based on the results of Tono-Pen Vet tonometer, all drugs reduced the IOP immediately after use; however, the effects of bupivacaine and lidocaine on IOP were much lower than that of tetracaine and proparacaine. The average duration of corneal anesthesia were 20, 15.5, 7.5 and 21 minutes for tetracaine, bupivacaine, lidocaine, and proparacaine, respectively. It is concluded that IOP reduction by local anesthetics when Tono-Pen Vet is used is much greater than the ICare tonometer measurements. Also, the reduction of IOP with each of the devices when tetracaine or proparacaine is used is greater than when bupivacaine or lidocaine is used.

Authors and Affiliations

Arman Emrarian,Ali Asghar Sarchahi,

Keywords

Related Articles

A case of atrial fibrillation in a horse: clinical and electrocardiographic features

Atrial fibrillation (AF) was detected as an incidental finding in a 14 years old brood mare horse which was maintained for student education in the teaching hospital, Faculty of Veterinary Medicine, Mashhad. Irregular he...

Detection of Mycoplasma bovis in bulk tank milk samples by nested PCR in Mashhad, Iran

Mycoplasma bovis is a highly contagious major mastitis pathogen with multiple clinical presentations in dairy cows. This kind of mastitis does not respond to available antibiotics and actually there is no effective thera...

Case-control study on risk factors associated with brucellosis in aborted cattle of Jimma zone, Ethiopia

Brucellosis is one of the most important causes of abortion in cattle resulting in significant economic losses and public health concerns in the developing countries. A case-control study was conducted from October 2016...

Growth response of Salmonella typhimurium as a function of temperature, pH, organic and inorganic acids, and NaCl concentration

Salmonella is still one of the most important pathogens related with foodborne outbreaks.This study was designed to examine the combined effects of different levels of pH (7.4, 6.4, and 5.4), acids (acetic, citric an...

Sexual Dimorphism in Clinical Chemistry and Profile of Hybrid Catfish (Heterobranchus longifilis)

Sex has been reported to influence  the clinical chemistry of several species of fish. Whether sex impacts serum biochemistry composition and electrolyte profile of Heterobranchus longifilis is not well captured in the...

Download PDF file
  • EP ID EP722386
  • DOI -
  • Views 135
  • Downloads 2

How To Cite

Arman Emrarian, Ali Asghar Sarchahi, (2020). Effect of four local anesthetics (tetracaine, bupivacaine, lidocaine and proparacaine) on intraocular pressure in rabbits- Comparison of an applanation and a rebound tonometer. Iranian Journal of Veterinary Science and Technology (IJVST), 12(1), -. https://europub.co.uk/articles/-A-722386