Effect of Heroin Use on Liver Enzymes
Journal Title: Journal of Advances in Biology & Biotechnology - Year 2016, Vol 5, Issue 1
Abstract
Aim: A study of enzymes in the liver of heroin addicts enables a precise overview of the degree of the liver damages caused by heroin abuse, deviation of enzymes from the normal healthy values and degree of presence of hepatitis in intravenous heroin abusers. Materials and Methods: The levels of three liver enzymes alkaline phosphatase, alanine aminotransferase and aspartate aminotransferase in blood samples of the heroin addicts were investigated. The liver function tests were conducted on 25 serum samples of heroin addicts and 25 control serum samples. The age of male subjects was between 25-45 years. Results and Discussion: In the investigated group of heroin addicts, serum samples showed changes in the enzyme levels. Nearly 52% heroin addicts showed elevated liver enzymes and 32% out of 52% heroin addicts showed elevated enzyme levels with positive HCV and HBsAg tests. The established changes correlated with the duration of heroin abuse and presence of HBV and HCV positive results. The study showed that the most prominent change is the elevation of enzymes and it is the only direct consequence of liver damage due to heroin use.
Authors and Affiliations
S. Farooqi, T. Altaf, H. Mubeen
Keywords
Related Articles
- EP ID EP351722
- DOI 10.9734/JABB/2016/22047
- Views 64
- Downloads 0
A Morphometric Study on Two Groups of Brown Trout (Salmo trutta) Population, 1758 in Northern Region of Albania
This study was carried out to determine morphological differences between two brown trout (Salmo trutta Fario) populations of two Alpine rivers in Northern Albania: Cem River and Valbona River. Fifty five single individu...
Predicting CD4+ T Lymphocyte Count Using IgG and Total Lymphocyte Count in Newly Diagnosed HIV Infected Patients in Specialist Hospital Sokoto North West Nigeria
CD4+ T cell count and viral load monitoring are expensive and unavailable to most human immunodeficiency virus (HIV) infected people in Africa. There is a need to have another marker of HIV infection that is less resourc...
Histo-architectural Comparative Analysis of the Hypothalamus of Bat (Eidolon helvum) and Wistar Rat (Rattus norvegicus)
Aims: The aim of this study was to compare the histo-architectural variation (if any) on hypothalamus of both Rat (Rattus norvegicus) and Bat (Eidolon helvum). Study Design: The histological and histochemical investigati...
In vitro Rapid Regeneration of Betel Vine (Piper betle L.)
The experiment was conducted on betel vine (Piper betle L.) for in vitro regeneration in Biotechnology Lab. of the Department of Biotechnology, Sher-e-Bangla Agricultural University, Bangladesh from the period of July 20...
Prevalence of Malaria Parasitaemia in Three Selected Local Government Areas of Niger State, North Central, Nigeria
Introduction: Malaria- a parasitic protozoan infection, caused by Plasmodium species- is a major public health challenge in Africa. Aside hundreds of thousands of annual deaths attributable to malaria, lots of valuable m...