Effect of Hydrocarbon Chain Length in 1,2-Alkanediols on Percutaneous Absorption of Metronidazole: Toward Development of a General Vehicle for Controlled Release
Journal Title: AAPS PharmSciTech - Year 2014, Vol 15, Issue 2
Abstract
MTZ was purchased from ZhongAn Pharmaceutical, Tianjin, China. 1,4-Cyclohexanediol was obtained from Sigma-Aldrich (St. Louis, MO, USA). 1,2-Propanediol, 1,2-butanediol, 1,2-pentanediol, and 1,2-hexanediol are readily available from various commercial sources. Klucel® MF was obtained from Hercules, Inc. (Wilmington, DE, USA). All other chemicals are of analytical grade.
Authors and Affiliations
Nan Li, Weibu Jia, Yan Zhang, Michelle C. Zhang, Fengping Tan, Jerry Zhang
Keywords
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