EFFECT OF INTRAVENOUS FLUID SUPPLEMENTATION IN HEALTHY TERM NEONATES WITH NON-HEMOLYTIC HYPERBILIRUBINEMIA
Journal Title: INTERNATIONAL JOURNAL OF ADVANCED MEDICINE - Year 2018, Vol 2, Issue 6
Abstract
Objective: The objective of this study was to evaluate the effect of intravenous uid supplementation in healthy term neonates with non-hemolytic hyperbilirubinemia receiving phototherapy. Study Design: Randomized controlled trial conducted in a tertiary level neonatal care unit of a teaching institute in Kota. Methods: A total of 100 healthy term neonates with non-hemolytic hyperbilirubinemia between 2nd to 14th day of life (total serum bilirubin [TSB] >15 mg/dL [256 μmol/L] to <25 mg/dL [428 μmol/L]) were randomized to two groups. Group I (case group, n=50) received 1/3rd the maintenance intravenous uid in addition to breastfeeding and phototherapy. Group II (control group, n=50) received only breastfeeding and phototherapy. The duration of phototherapy was compared. Results: Both the groups were comparable with respect to mean birth weight, gestational age, gender, mode of delivery, age at admission, admission weight, percentage of weight loss at admission, and TSB at inclusion. There was a signicant difference in the duration of phototherapy between the two groups (mean [standard deviation (SD)] Group I, 124.48(6.86)h and Group II, 168.67(7.63)h, p<0.05). Conclusion: Intravenous uid supplementation in healthy breastfed term neonates with non-hemolytic hyperbilirubinemia signicantly reduces the duration of phototherapy.
Authors and Affiliations
Dr. Anisha Meena, Dr. Gopikishan Sharma, Dr. A. L. Bairwa
Keywords
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