Effect of letrozole on masculinization of Siamese fighting fish (Betta splendens)
Journal Title: Journal of Applied and Natural Science - Year 2015, Vol 7, Issue 1
Abstract
The aim of this study was to evaluate the effect of letrozole (a non-steroidal aromatase inhibitor) on masculinization of Siamese fighting fish (Betta splendens). Different doses of letrozole 50, 100, 150 and 200 ppm (mg/kg feed) were incorporated into diet and fed for periods of 30, 40 or 50 days. Immersion treatment of letrozole at selected doses (250, 500, 750 and 1,000μg/l) for 3 h each on third, fifth and eighth day-post-hatching (dph) (Trial 1) and fourth, sixth and eighth dph (Trial 2) was given.The oral administration of letrozole for 30, 40 or 50 days did not have any significant effect on the sex ratio of B. splendens. The immersion treatment of letrozole induced 100% masculinization at 500 and 1000μg/l in trial 1, while it yielded only 66.66 and 90% male population at 500 and 1000 μg/l in Trial 2. The dietary administration of letrozole for 30 and 50 days caused tail deformities and/or rudimentary and absence of dorsal fin. The progeny testing of males from letrozole treated (both oral and immersion) groups indicate that the sex ratio of progenies of each of the males tested did not differ significantly from that of control, indicating that all those males carried XY genotype. Letrozole treatments suppressed ovarian development (atretic oocytes were common). However, the testicular development was unaffected. The study revealed that immersion treatment of letrozole was more effective in inducing masculinization of B. splendens than the oral administration of letrozole.
Authors and Affiliations
Milind B. Katare, N. Basavaraja, Harshavardhan D. Joshi, Chirom Archna
Keywords
Related Articles
- EP ID EP283107
- DOI 10.31018/jans.v7i1.627
- Views 83
- Downloads 0
Eco-friendly dyeing of wool and pashmina fabric using Quercus robur L. (fruit cups) dye and Salix alba L. (wood extract) mordant
Study was conducted to investigate the dyeing potential of Quercus robur L. (fruit cups) dye and Salix alba L. (wood extract) mordant on wool and pashmina fabrics. The experiment was conducted keeping in view the environ...
Impact of biotic and abiotic factors on lac production and peoples’ livelihood improvement in India-An overview
In India, Madhya Pradesh is the third largest lac producing state after Chhattisgarh and Jharkhand, as they contribute 12, 16 and 60%, respectively in total country’s lac production. Lac is produced in ten out of eleve...
Citric acid: A potential permeabilizer against multiple drug resistance enteropathogenic Escherichia coli
Enteric diseases enter through the mouth and are usually spread by contaminated food, water or contact with contaminated vomit or feces. Enteric infection encompasses all the infections of the intestinal tract. These int...
A study on socio- economic condition of Tharu tribes in Bahraich district of Uttar Pradesh in India
As per the census of 2011 the tribal population consists of 8.6% while it was 8.2% according to the census of 2001 in India. This paper addresses the socio-economic status of Tharu tribes in Bahraich district of Uttar Pr...
Effect of ethrel spray on the ripening behaviour of mango (Mangifera indica L.) variety 'Dashehari'
An experiment was carried out to investigate the effect of post harvest spray of different concentrations (100, 200, 400, 600 and 800 ppm) of ethrel (2-chloroethyl phosphonic acid) on ripening and colour development in ‘...