Effect of Long-term Topical Application of 0.005% Latanoprost on Intraocular Pressure Uncontrolled by Multiple or Single Drug Therapy in Dogs with Secondary Glaucoma
Journal Title: Journal of Veterinary Science & Medical Diagnosis - Year 2017, Vol 6, Issue 1
Abstract
Purpose: To evaluate the effect of long-term topical application of 0.005% latanoprost on intraocular pressure (IOP) uncontrolled by multiple or single drug therapy in dogs with secondary glaucoma. Animals Studied: Twenty-seven dogs with secondary glaucoma. Procedure: Baseline IOP was measured before the start of 0.005% latanoprost therapy. The iridocorneal angle (ICA) was measured and graded as open, slightly narrow, narrow or closed. The effect of 0.005% latanoprost on IOP was followed for a minimum of two months. Dogs were classified as responders if IOP decreased with treatment or as non-responders if there was no change in IOP. Results: IOP did not decrease in three dogs (11%). It decreased initially but subsequently increased over time in 21 dogs (78%). IOP remained <25 mmHg for more than 60 months in 3 dogs (11%). No correlation between ICA grade and IOP reduction from baseline was observed. Conclusions: Topical application of 0.005% latanoprost resulted in long-term control of IOP in 11% of the dogs. The remaining dogs showed either no response or just a temporary decrease in IOP with topical 0.005% latanoprost treatment.
Authors and Affiliations
Kumiko Kato, Alexandra van der Woerdt
Keywords
Related Articles
- EP ID EP356370
- DOI 10.4172/2325-9590.1000218
- Views 59
- Downloads 0
Effect of Age, Gender, and Season on Hematological Parameters in Quarter Horses
Objective: To determine the effect of age, sex and season on some selected hematological parameters of quarter horses (QH) from the North East of Mexico. Materials and Methods: Blood samples of 205 healthy QH were collec...
Sequestrum in a Lymph Node in Contagious Bovine Pleuropneumonia (CBPP) Infection without Lung Lesions: A Case Report
Contagious bovine pleuropneumonia (CBPP) is a highly contagious disease of ruminants caused by Mycoplasma mycoides subsp. mycoides (Mmm), with a major impact on livestock production and a potential for rapid spread. It i...
Investigation of Infectious Bronchitis Virus Strains by Real Time RT-PCR and S1 Gene Sequencing in Broilers
In this study, detection of infectious bronchitis virus (IBV) from chicken tracheal swab samples by real time RT-PCR, which was reported as a rapid and sensitive virus detection method, was aimed. Phylogenetic relations...
Successful Treatment of Feline Panleukopenia: A Guideline For Rescuers and Veterinarians, Part I
We present a successful approach for treating feline panleukopenia, a fatal and highly contagious disease. It involves recognizing the disease early though the uses of parvo test kits or low neutrophil count; applying th...
Identification of Foot and Mouth Disease Virus Strains Originating from Multispecies Susceptible Animals
A first in country trail of detection, isolation and identification of Foot and Mouth disease virus (FMDV) strains was conducted in Qatar during the year 2015-2016. Using rRT-PCR and RT-PCR assay, 31/131 (23%) subject an...