Effect of maternal vitamin A supplementation on retinol concentration in colostrum
Journal Title: Jornal de Pediatria - Year 2015, Vol 91, Issue 1
Abstract
Objective To investigate the effect of vitamin A supplementation on the retinol concentration in colostrum under fasting and postprandial conditions. Methods This was a quasi-experimental study, with before and after assessments, conducted with 33 patients treated at a public maternity hospital. Blood and colostrum samples were collected under fasting conditions in the immediate postpartum period. A second colostrum collection occurred two hours after the first meal of the day, at which time a mega dose of 200,000 IU of retinyl palmitate was administered. On the following day, the colostrum was collected again under fasting and postprandial conditions. Serum and colostrum retinol concentrations were determined by high performance liquid chromatography. Results The serum retinol concentration was 37.3 (16.8-62.2) μg/dL, indicating adequate nutritional status. The colostrum retinol concentration before supplementation was 46.8 (29.7-158.9) μg/dL in fasting and 67.3 (31.1-148.7) μg/dL in postprandial condition (p < 0.05), showing an increase of 43.8%. After supplementation, the values were 89.5 (32.9-264.2) μg/dL and 102.7 (37.3-378.3) μg/dL in fasting and postprandial conditions, respectively (p < 0.05), representing an increase of 14.7%. Conclusions This study demonstrated that maternal supplementation with high doses of vitamin A in postpartum resulted in a significant increase of the retinol concentration in colostrum under fasting conditions, with an even greater increase after a meal.
Authors and Affiliations
Evellyn Grilo
Keywords
Related Articles
- EP ID EP561136
- DOI 10.1016/j.jped.2014.05.004
- Views 79
- Downloads 0
Sensitivity and specificity of different measures of adiposity to distinguish between low/high motor coordination
Objective This study aimed to determine the ability of different measures of adiposity to discriminate between low/high motor coordination and to evaluate the relationship between different measures of adiposity and moto...
Signs and symptoms associated with digestive tract development
Objective To analyze the development and prevalence of gastrointestinal signs and symptoms associated with the development of the digestive tract, and to assess the measures aimed to reduce their negative impacts. Sourc...
Body image dissatisfaction and dietary patterns according to nutritional status in adolescents
Objective There is a lack of data on the association between body self-perception and eating patterns in Brazil. Thus, this study aimed to explore the relationship between body image dissatisfaction and eating patterns b...
Low FODMAPs diet for functional abdominal pain disorders in children: critical review of current knowledge
Objective This narrative review aimed to provide practitioners a synthesis of the current knowledge on the role of a low Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols diet in reducing symptoms as...
Smoking: it's still a big problem in children with asthma
Smoking is an independent risk factor for the development of asthma symptoms,1 loss of lung function,2 and asthma exacerbations.3 The mechanisms of smoking-related lung disease can include increased small-airway inflamma...