Effect of Multivisceral Resection on Health Status and Survival of Patients with Locally Advanced Gastric Cancer
Journal Title: HASEKİ TIP BÜLTENİ - Year 2017, Vol 55, Issue 4
Abstract
Aim: Gastric cancer is the fifth most common cancer and the second leading cause of cancer-related deaths. Adjacent organ invasion is frequently observed in cases of gastric cancer which is often diagnosed in advanced stages in the Western countries. It is aimed to evaluate the effects of gastrectomy with multivisceral resection on health status and survival of patients with locally advanced gastric cancer. Methods: The prospectively recorded data of 445 operated patients in the General Surgery Clinic at Dokuz Eylül University due to gastric cancer were reviewed. A total of 164 patients with locally invasive tumor detected during laparotomy or those in pT4 status according to post-resection pathologic staging were included in the study. Results: One hundred and twenty patients underwent gastrectomy, 24 patients underwent gastrectomy with multivisceral resection, and 20 patients underwent palliative procedure. The patient groups were compared for demographic data, tumor location, preoperative biochemical analysis, hemoglobin values, and survival. The patients with palliative procedures were found to be significantly disadvantaged in terms of survival. There were no differences in the rates of R0 resection and postoperative complication between multivisceral resection group and only gastrectomy group. It was determined that survival of patients with multivisceral resection was significantly longer than palliative surgery patients. Conclusion: Multivisceral resection in patients in whom R0 resection is possible, in those with a platelet/lymphocyte ratio of <130, neutrophil/lymphocyte ratio of <2.4, and with fewer than six metastatic lymph nodes, may provide increased survival periods without additional morbidity burden in experienced hands.
Authors and Affiliations
Serhan Derici, Koray Atilla, Sülen Sarıoğlu, Seymen Bora
Keywords
Related Articles
- EP ID EP251845
- DOI 10.4274/haseki.58066
- Views 89
- Downloads 0
Quantitative Analysis of Osteoporotic Vertebral Fracture Risk on Pre-Existing CT
Aim: Recent research has shown that the measurement of vertebrae bone density on computed tomography for diagnosis of osteoporosis is associated with dual energy X-ray absorptiometry. Our aim was to compare vertebra bone...
A Rare Cause of Upper Gastrointestinal Bleeding: Brunner’s Gland Hamartoma
Brunner’s gland hamartoma is a submucosally localized and rarely encountered benign condition. Majority of cases are asymptomatic. Generally, it is diagnosed incidentally during endoscopic examinations of the upper gastr...
Laparoscopic Abdominal Surgery Under Regional Anesthesia: A Retrospective Evaluation
Aim: Laparoscopic abdominal surgical procedures are usually performed under general anesthesia. In this retrospective study, we aimed to evaluate laparoscopic surgical operations performed with regional anesthesia. Metho...
Effect of Antiepileptic Drug Treatment on Thyroid Hormone Levels in Epilepsy Patients
Aim: Antiepileptic drugs (AEDs) can have an effect on hormone metabolism and function, and alter serum levels of some hormones. This study aimed to determine the effects of AEDs on thyroid function test results in epilep...
Acute Kidney Injury and Chronic Kidney Disease: A Bidirectional Road
Acute kidney injury (AKI) and chronic kidney disease (CKD) have many common points regarding risk factors, etiology, clinical and laboratory factors. We aimed in this review to discuss the outcome, the risk of CKD, cardi...