Effect of Myoinositol (MI) In Patients of Polycystic Ovarian Disease (PCOD)
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 10
Abstract
Polycystic ovarian disease (PCOD) is a common endocrine disorder. Majority of young females are affected. Insulin resistance along with dysfunction of hypothalamo pituitory adrenal axis is a key etiological factor in development of all manifestations of PCOD. They present with irregular menses, infertility, obesity, hirsutism, acanthosis Nigricans etc. MI(MI),an insulin sensitizer is widely accepted treatment modality. Data suggests variable responses to MI. So we aimed to study efficacy of MI in PCOS. Here 32 cases are recruited those diagnosed by using Rotterdam’s criteria .BMI, menstrual irregularity, infertility, hirsutism, acanthosis Nigricans, acne were common presenting features. Hormonal & biochemical profile was studied S.LH (Luteinizing Hormone), FSH (Follicle stimulating hormone), Serum. Prolactin levels, Serum Insulin levels were studied. Weight loss, menstrual regularity, LH/FSH Ratio, HOMA Index was studied initially & compared all parameters after 3 months of treatment. In our study BMI mean was 26.71, after MI treatment it became 25.6.Differences of all parameters before & after MI suggests, there is significant reduction in BMI & LH/FSH ratio. Other parameters are not affected by MI. It suggests MI has been effective in reducing BMI & LH/ FSH ratio significantly. But there was no change in HOMA index. So MI can be good supportive treatment option in PCOD. The present study gives us idea about efficacy of MI treatment in PCOD cases & will be useful in patient treatment schedules.
Authors and Affiliations
Dr Jayshree Awalekar
Keywords
Related Articles
- EP ID EP212669
- DOI -
- Views 143
- Downloads 0
A Study of Ocular Manifestations in Neurocutaneous Syndromes
Phakomatosis (from the Greek ‘Phakos’ meaning mother spot or mole or freckle) is a group of hereditary disorders characterized by the presence of hamartias and hamartomas involving different organ systems derived from al...
Medical Technology: Less Use and More Misuse
This paper deals with ethical conundrum involved in the surge of high end technology invading medical equipment and gadgets. The pace of ethical understanding and formulation under strips the momentum of value added medi...
Comparison between clinical and ultrasound finding in patients with vitreous hemorrhage
Vitreous hemorrhage is defined as extravasation of blood into one of the several potential spaces formed within and around the vitreous body1 . Vitreous hemorrhage can be caused by the pathological mechanisms like disrup...
Pneumatization of the Sphenoid Sinus: A Computed Tomographic Study
Aim: The present study was done with a purpose to find out variations of sphenoid sinus and its related structure and compare these findings with other studies to note any racial differences among them. Material & Method...
Role of MRI and Doppler Sonography in Evaluation of Soft Tissue Masses: A Comparative Study
Introduction: MRI is well established to provide excellent spatial and anatomical evaluation of soft tissue masses, however grey scale and Doppler evaluation may provide sufficient information to differentiate benign and...