Effect of Myoinositol (MI) In Patients of Polycystic Ovarian Disease (PCOD)
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 10
Abstract
Polycystic ovarian disease (PCOD) is a common endocrine disorder. Majority of young females are affected. Insulin resistance along with dysfunction of hypothalamo pituitory adrenal axis is a key etiological factor in development of all manifestations of PCOD. They present with irregular menses, infertility, obesity, hirsutism, acanthosis Nigricans etc. MI(MI),an insulin sensitizer is widely accepted treatment modality. Data suggests variable responses to MI. So we aimed to study efficacy of MI in PCOS. Here 32 cases are recruited those diagnosed by using Rotterdam’s criteria .BMI, menstrual irregularity, infertility, hirsutism, acanthosis Nigricans, acne were common presenting features. Hormonal & biochemical profile was studied S.LH (Luteinizing Hormone), FSH (Follicle stimulating hormone), Serum. Prolactin levels, Serum Insulin levels were studied. Weight loss, menstrual regularity, LH/FSH Ratio, HOMA Index was studied initially & compared all parameters after 3 months of treatment. In our study BMI mean was 26.71, after MI treatment it became 25.6.Differences of all parameters before & after MI suggests, there is significant reduction in BMI & LH/FSH ratio. Other parameters are not affected by MI. It suggests MI has been effective in reducing BMI & LH/ FSH ratio significantly. But there was no change in HOMA index. So MI can be good supportive treatment option in PCOD. The present study gives us idea about efficacy of MI treatment in PCOD cases & will be useful in patient treatment schedules.
Authors and Affiliations
Dr Jayshree Awalekar
Atypical Atrial Flutter in a Patient with Ischemic Stroke – A Rare ECG Finding
Electrocardiogram (ECG) changes are observed in patients with acute stroke and may create confusion with ECG changes found in cardiac disorders. Various ECG changes are observed in patients with acute stroke including rh...
Prospective Study to find out whether Continuous Curvilinear Capsulorrhexis is mandatory to achieve a Good Result in Phacoemulsification
Aim of this study is to find out whether it is mandatory to do Curvilinear continuous capsulorhexis(CCC) to achieve a good result in phacoemulsification. Materials and methods consisted of a prospective, randomised study...
A Comparative Study of Large Vessel Ischemic Stroke and Lacunar Stroke
Stroke is a global epidemic and an important cause of morbidity. Stroke or cerebrovascular accident is defined as abrupt onset of focal Neurological deficit which is attributable to a focal vascular cause. Ischemic strok...
The Effect of Counseling and Providing Temporary Waste Shelter on Behavior of Household Waste Management
Background: Waste management will not be carried out accurately without the participation of all parties, namely the community, business actors and the government. This study aims to determine the effect of counseling an...
To Compare the Efficacy & Safety of Nerve Stimulation Method with Ultrasound Guidance along With Nerve Stimulation alone for Supraclavicular Brachial Plexus Block
There are several well-established techniques for performing peripheral nerve blocks including paresthesia, nerve stimulation and by using ultrasound. Those advocating the use of nerve stimulators claim that apart from a...