Effect of Nescafe 3 in 1TM and Cowbell TM Sachet Coffees on Body Weight, Urea, Creatinine, Lipid and Enzyme Profiles and Electrolytes in Healthy Albino Wistar Rats
Journal Title: The Journal of Middle East and North Africa Sciences - Year 2017, Vol 3, Issue 9
Abstract
Background and Objectives: Coffee the source of caffeine is consumed globally. The amount of caffeine in food product varies depending upon the serving size, type product and production method (Elmaadawy et al., 2015). Caffeine, one of the several ingredients in foods is capable of exerting a physiological and pharmacological effect. Nescafe is a brand of instant coffee made by Nestle. It comes in different product forms (Elmaadawy et al., 2015). Nescafe 3 in 1TM Ghana PLC and Cowbell Promasidor Nigeria Limited Coffee are brands of coffee widely consumed in Nigeria. From a public health point of view little seems to be understood about the health benefits. The purpose of this work is to evaluate the effect of Nescafe 3 in 1TM and cowbell TM coffees on body weight, serum urea, creatinine, lipid, and enzyme profile in healthy rats. Material and Methods: Thirty healthy male albino rats (150±5.35g) were assigned into five groups of six rats. Group 1 served as control fed with basal diets; groups 2 and 3 Nescafe 3 in 1 high dose, 770mg/kg, and Low dose, 510mg/kg of body weight. Group 4 and 5 cowbell coffee high doses, 620mg/kg and low dose 310mg/kg. All administration was done orally, water and food given ad libitum. The treatment lasted for 30days. At the end of the period, the animals were sacrificed and blood samples were collected for analysis. Result: Nescafe 3 in 1TM low dose cause significant (p<0.01) increase in body weight while cowbell coffee TM treated groups caused a decrease in body weight. There was an increase in AST, creatinine, HDL, serum urea, K+, HCO3- levels in Nescafe 3 in 1TM while Na+, Cl- were decreased in cowbell coffee TM compared with control. Conclusion: Nescafe 3 in 1TM coffee caused increased body weight although the high dose group was not statistically significant while the consumption of cowbell coffee TM caused a significant decrease. These differences might result from the composition of these coffees especially their coffee content. Further investigation might be necessary on these brand sachet coffees.
Authors and Affiliations
O. O. Okwari, E. A. Alagwu, C. O. Edoga, S. A. Lelei, G. A. Ekonesi
Keywords
Related Articles
- EP ID EP212585
- DOI -
- Views 161
- Downloads 0
Interferences of Different Concentration of Detergent Solution on Glucose Assays in Clinical Chemistry
The pre-analytical stage is so complex that a mistake at any step often becomes apparent in the analytical or post-analytical phase. Many medical laboratorians do not carefully evaluate the suitability of the pre-analyti...
How to Properly Understand Enhanced Recovery After Surgery?
Enhanced recovery after surgery (ERAS) has become a hot issue around the world (Lau, & Chamberlain, 2016). It aims to accelerate patients' recovery after surgery and prioritize the cost-effectiveness of health care. Gene...
An Analysis of Instructional Strategies in Teaching Oral Literature in Kiswahili among Selected Secondary Schools in Bungoma County
Teaching of oral literature in Kiswahili is an issue that has put teachers, students, scholars, and all the stakeholders in general on their toes. This issue has been a challenge to all stakeholders because the teaching...
Diagnostics for Design of Strategies of Production and Marketing of Honey Cosmetics
The objective of this research is to obtain a diagnosis with the application of tools that help to design production and commercialization strategies for a micro-enterprise of beekeepers that elaborates cosmetic products...
Solving Polynomial Inequalities with GeoGebra: Opportunities of Visualization and Multiple Representations
The main purpose of the present study is to investigate the ways students’ instrumentation of Computer Algebra System (CAS) can help promote their algebraic reasoning while solving polynomial inequalities. In addition, t...