Effect of periodic sildenafil dosage on intraocular pressure in patients with erectile dysfunction
Journal Title: Electronic Physician - Year 2017, Vol 9, Issue 9
Abstract
BACKGROUND AND AIM: Sildenafil is used to treat erectile dysfunction but it has association with some side effects. This study was conducted with the aim of investigating the effect of duration of taking sildenafil on intraocular pressure (IOP) in patients with erectile dysfunction. METHODS: The study population of this cross-sectional study were all males with erectile dysfunction referring to the urology clinic affiliated to Rafsanjan University of Medical Sciences (Kerman, Iran) over a one-year period (2015-2016) among whom 110 patients were included in the study. After medical examinations and required investigations, a weekly dose of 25-100mg sildenafil (50 mg per week on average) was prescribed for patients. IOP in these patients was measured by an ophthalmologist before, one month after and three months after taking medication respectively. Finally, data were analyzed by SPSS version 16 using repeated measures test. RESULTS: Mean IOP before taking medication as well as one month and three months after taking sildenafil was 14.88±1.3, 15±1.28 and 15±1.34 mmHg respectively. Analysis of results showed that the difference in IOP in various periods of measurement was significant (p<0.001). Mean IOP before taking sildenafil was significantly different from three months after taking it (p<0.001) and mean IOP one month after taking sildenafil was significantly different from three months after taking it (p=0.002). CONCLUSION: Results of this study indicated that taking sildenafil for three months increased IOP. Although these changes may not be clinically significant
Authors and Affiliations
Alireza Nazari, Yousof Taghavi Tabrizi, Mohammadreza Mokhtaree
Keywords
Related Articles
- EP ID EP329473
- DOI 10.19082/5229
- Views 99
- Downloads 0
Comparison the Effectiveness of Breastfeeding, Oral 25% Dextrose, Kangaroo-Mother Care Method, and EMLA Cream on Pain Score Level Following Heal Pick Sampling in Newborns: a randomized clinical trial
BACKGROUND: Today, it is considered that infants can feel pain, and it can have several adverse effects on their development. Although different interventions, such as skin-to-skin contact (kangaroo mother care method),...
Deep venous thrombosis in elderly patients as a surgical emergency at King Abdulaziz University Hospital, Jeddah, Saudi Arabia
BACKGROUND: Deep venous thrombosis (DVT) is a condition that occurs frequently among surgical, as well as acutely ill hospitalized medical patients, and is responsible for significant morbidity and mortality in hospitali...
Development and implementation of Persian test of Elderly for Assessment of Cognition and Executive function (PEACE).
A considerable segment of the elderly population in Iran is illiterate, and it seems the existing neuropsychological screening tests are not very useful for detecting dementia in illiterate participants. The purpose of t...
Quality assessment of clinical education services in teaching hospitals located in Kerman, Iran.
Clinical education is one of the most important components of the resource generation function of health systems, and it has a very important role in graduates' competency with respect to effective, practical education....
The relationship between organizational commitment and nursing care behavior
INTRODUCTION: Nursing care encompasses physical, emotional, mental and social needs, in order to improve a patient's health and wellbeing. Caring is the central core and the essence of nursing. The important issue of car...