Effect of potassium dichromate intake on water consumption and toxic amount intake, in female rats, Rattus norvegicus (exposure on threegenerations).
Journal Title: Human & Veterinary Medicine - International Journal of the Bioflux Society - Year 2010, Vol 2, Issue 1
Abstract
Material and methods: The study was carried out on three generations of female rats, each generation comprising 28 white Wistar adult female rats, divided in three experimental (E) groups, exposed to 25 ppm Cr – LOAEL (E1), 50 ppm Cr (E2), 75 ppm Cr (E3) and one control (C) group - tap water. Results: It pointed out significant decrease of water daily mean consumption in experimental groups comparative to C group, inversely, significantly correlated with the exposure level, in F0, F1 and F2 generations, the mean daily water intake decreasing with the increase of the number of generations exposed, the lowest being found in the case of F2 generation, followed by F1 generation and F0, the differences being insignificant. Also hexavalent chromium intake was calculated, F2 generation having the poorest appetite for water, received the smallest amount of toxic, but yet not undermining the gravity of exposure in F2 generation, due to parental exposure factors.
Authors and Affiliations
Snejana Petrovici, Alexandra Trif, Milca Petrovici, Eugenia Dumitrescu, Romeo Cristina, Camelia Tulcan
Keywords
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