Effect of pre-operative rectal diclofenac suppository on post operative analgesic requirement in cleft lip palate repair

Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 3

Abstract

Respiratory depression, sedation, nausea and vomiting are common problems associated with the use of opioid analgesics during surgeries. Diclofenac, a non‑steroidal anti-inflammatory drug (NSAID) can be an effective and safe option. The Aims and objectives in the present study was done to assess the efficacy and safety of rectal diclofenac, used in cleft palate repair for post‑operative analgesia. The Materials and methods in a prospective randomized double blind study were done including 60 children’s posted for cleft lip and palate repair. The patients were divided into Group A (did not receive any suppository) and Group B (received diclofenac suppository at 1mg/kg dose before induction and intubation). Pain assessment was done using Modification of Objective pain scale. In Results the Mean age in Group A and Group B was 27.13±17.18 and 33.60±20.71 months respectively. In group A, 80% children require rescue analgesia as compared to Group B (26.66%). There was a significant reduction in pain score at 90 minutes and at 2 hours in Group B as compared to Group A (p<0.05). In Conclusion the Administration of rectal diclofenac can be an alternative in reducing postoperative pain. Keywords: rectal diclofenac, postoperative pain, cleft lip palate repair.

Authors and Affiliations

Dr Brijmohan Sahu, Dr Chandra Shekhar Mishra

Keywords

Related Articles

Association of CYP17 Gene Polymorphism with Carcinoma of Prostate

The CYP17 gene encodes for the Cytochrome P450c17ɑ enzymes 17ɑ hydroxylase, 17-20 lyase in testosterone synthesis. There is a polymorphism (T to C substitution) in the 5’ untranslated region of CYP17 gene, providing an i...

Serum Leptin Level in Diabetes Mellitus : A Case Control Study in India

Abstract: It is a universal endocrine disorder and both its incidence and prevalence are alarmingly increasing day by day. Leptin is a hormone communicating information on the body fat store or energy reserve to the brai...

Staging and Prognostication Systems in Hepatocellular Carcinoma Cyriac Abby Philips

Liver cancer is the second most common cause of mortality among all cancers in the world. A holistic prognostic classification in hepatocellular carcinoma has not been unified yet. Many prognostic scoring systems have be...

Acute Kidney Injury- Incidence, Etiology and Clinical Outcome in A Multispeciality Hospital

Abstract: Acute kidney injury (AKI) is a syndrome of varied severity. It is characterized by a rapid (hrs to weeks) decline in the glomerular filtration rate (GFR) and retention of nitrogenous waste products such as bloo...

Adrenal tumours: Five years audit in a tertiary care centre

Adrenal gland is not handled routinely by the urologist because it is not so common. Surgical indications are not clearly defined. We present here the cases of adrenals who had undergone surgery for various indications i...

Download PDF file
  • EP ID EP371100
  • DOI -
  • Views 54
  • Downloads 0

How To Cite

Dr Brijmohan Sahu, Dr Chandra Shekhar Mishra (2016). Effect of pre-operative rectal diclofenac suppository on post operative analgesic requirement in cleft lip palate repair. Scholars Journal of Applied Medical Sciences, 4(3), 790-792. https://europub.co.uk/articles/-A-371100