Effect of Preoperative Use of Nepafenac and Flurbiprofen Eye Drops In Maintaining Mydriasis during Small Incision Cataract Surgery
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Objective: To compare the effectiveness of prophylactic administration of topical Flurbiprofen 0.03% and Nepafenac 0.1% in maintaining mydriasis during small incision cataract surgery (SICS). Materials and methods: This study was a prospective, randomized, double-blind comparative study in elderly cataract patients given topical flurbiprofen or nepafenac prior to SICS. Horizontal and vertical diameters of pupil were measured at the beginning and end of surgery, and the mean values were compared across the two groups. Unpaired t-test was used to analyse the results. Results: A total of 70 eyes of cataract surgery patients, 35 in each group were included in the study. The mean vertical diameter of the two groups were similar whereas mean horizontal diameter was greater in nepafenac group than flurbiprofen group (p=0.001). Significant differences were seenafter IOL implantation, with the nepafenac group having the larger mean diameters in both horizontal (P = 0.003) and vertical (P = 0.000) pupillary measurements. Conclusion: Topical Nepafenac is more effective in maintaining mydriasis than Flurbiprofen.
Authors and Affiliations
Dr P. Pradeep, Dr Rema Raquel Samuel . T
Keywords
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- DOI 10.9790/0853-1801191623.
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