EFFECT OF RISPERIDONE AND CLOZAPINE ON EXECUTIVE FUNCTIONS IN FIRST EPISODE SCHIZOPHRENIA
Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 7, Issue 3
Abstract
Aims: To compare the effect of risperidone and cloazpine on executive functioning in treatment naïve first episode schizophrenia. Methods: A total of 55 treatment naïve first episode patients of schizophrenia as per ICD-10 criteria, were enrolled for the study. Baseline assessment for executive functioning was carried out with TMT- A & B. Clozapine and risperidone were used in the range of 200-600mg/ day and 4- 8 mg/day respectively for 6 months. Results: There was significant improvement in executive functioning in both the groups and the results were statistically significant for clozapine on TMT-B. Conclusion: The findings of current study show that both risperidone and clozapine lead to improvement in executive functioning in first episode of schizophrenia and clozapine fared better than risperidone.
Authors and Affiliations
Dr. Ajeet Sidana, Dr. B. S. Chavan, Dr. Sukhtej Sahni
Keywords
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