Effect of Seabuckthorn leaves on Antioxidant and Microsomal Enzymes in poultry birds
Journal Title: The Journal of Phytopharmacology - Year 2018, Vol 7, Issue 5
Abstract
In vivo studies on broiler birds were carried out to evaluate effect of aflatoxin and seabuckthorn leaves on microsomal enzyme system, antioxidant enzymes and biochemical parameters i.e. serum triglyceride, total plasma protein, aminopyrine demethylase, aniline hydroxylase, NADPH cytochrome P450 reductase, catalase, LPO, superoxide dismutase, GSH, blood urea nitrogen (BUN) and creatinine levels in poultry. The poultry birds were divided into six groups containing six birds each. Aflatoxin (400 ppb) and seabuckthorn leaves (10000ppm) was administered continuously in poultry feed. Aflatoxin increased serum triglyceride, blood urea nitrogen and creatinine levels where as seabuckthorn leaves supplementation at 10000ppm significantly decreased triglyceride (P<0.05), blood urea nitrogen (P<0.05) and creatinine levels in birds. Toxin decreased liver, kidney and blood superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH) activity, whereas, seabuckthorn leaves (SBTL) increased the activity of these enzymes as compared to control group. The level of lipid peroxidation was significantly increased in the toxin exposed group and decreased in case of SBTL. The activity of Aminopyrine demethylase and Aniline hydroxylase increased, while the activity of NADPH cytochrome P450 reductase is decreased in case of toxin group whereas in case of seabuckthorn leaves exposed group showed no significant change in case of aminopyrine demethylase and NADPH cytochrome P450 reductase, however, the activity of Aniline hydroxylase decreased. On the basis of present study, it could be concluded that the seabuckthorn leaves reduced the effect of Aflatoxin which produced oxidative stress by altering the levels of antioxidant enzymes of liver and kidney in adult poultry birds.
Authors and Affiliations
Arti Ghabru, Shivani Chauhan, C. Varshneya
Keywords
Related Articles
- EP ID EP49843
- DOI -
- Views 216
- Downloads 0
Pharmacognostical and Phytochemical Evaluation of Gandhakadi Yoga
Thalassemia is one of the most challenging form of Haematological disorders. Gandhakadi Yoga is an Ayurvedic medicine comprising of SHUDDHA GANDHAKA (Sulphur), VIDANGA (Embelia ribes Burm.f.), AGASTYA PATRA (Sesbaniya...
Isolation and characterization of Lactobacillus spp. from curd and its pharmacological application in probiotic chocolate
The isolated and identified bacteria from curd sample are of Lactobacillus sp. The bacteria of this spp. are lactic acid producers. These sp. resembles to Lactobacillus acidophilus. A probiotic is a microorganism known...
Butyrylcholinsterase inhibitors from two Ficus species (Moraceae)
Alzheimer’s disease (AD) is the most common form of dementiaand mainly afflict people over 65 years of age. AD is characterized by a progressive memory loss that leads to a profound emotional disturbance in later stage...
Evaluation of some plant extracts for nemato-toxic potential against juveniles of Meloidogyne incognita in vitro
Aqueous leaf extracts were utilized to assess the nematicidal or nematostatic property on second stage juvenile of Meloidogyne incognita. The juvenile were incubate at various concentration of leaf extract viz., 250, 50...
Assessment of antioxidant activity of Ficus asperifolia Miq aqueous extract - In vitro studies
Antioxidants play an important role in inhibiting and scavenging free radicals, thus providing protection to human against degenerative diseases. The aim of this study was to assess the in vitro antioxidant activity of...