EFFECT OF SHORT-TERM EXPOSURE TO FORMALIN ON KIDNEY FUNCTION TESTS OF STUDENTS IN NNEWI.
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 12
Abstract
Formaldehyde is extensively used to preserve cadavers in departments of anatomy. This study investigated the effect of short-term exposure to formalin on kidney function tests of students in Nnewi. There is paucity of information on this study in Nnewi hence the research. A total number of 50 students (male and female) aged 18-30 years, were randomly recruited into the pre and post experimental design study. Five milliliters (5mls) each of baseline and post-formalin exposure blood samples were collected from each participant and used for the analysis of biochemical parameters. Serum creatinine was determined by Jaffe Slot Alkaline Picrate method; urea by Berthelot method; uric acid by uricase method; Albumin by Bromocresol Green method; Total protein by Biuret method and electrolytes (Na+, K+, Cl-, and HCO3-) were determined using Ion Selective Electrode. Data obtained were analyzed using paired Students t-test. Results showed a significant increase in the mean serum urea (5.41±1.23 vs 4.49±1.17), uric acid (356.24±55.09 vs 306.96±57.90) , serum albumin, total protein and electrolytes (Na+, K+, Cl-, and HCO3-) levels post formalin exposure when compared with pre formalin exposure (p< 0.05) whereas, the mean serum creatinine level did not differ significantly post formalin exposure (p>0.05). In conclusion, short term exposure to formalin caused a significant increase in the mean serum levels of urea, uric acid, albumin, total protein as well as the electrolytes levels.
Authors and Affiliations
Ogbodo Emmanuel Chukwuemeka
Keywords
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