EFFECT OF SIDAGURI (SIDA RHOMBIFOLIA L) ON WOMAC SCORE ASSESSMENT IN OSTEOARTHRITIS PATIENTS
Journal Title: GJRA-Global Journal For Research Analysis - Year 2019, Vol 8, Issue 4
Abstract
Introduction : WOMAC scoring is one of the tools to assess the effectivity of therapy in osteoarthritis (OA) patients. The efficacy is proven if there is a decrease in WOMAC score after given therapy. Pain is the major complaint of OA patients, and it is usually connected with inammatory process. NSAIDs are the most common therapy given in OA to reduce pain. Sidaguri (Sida rhombifolia L) is one of the medicinal plants which had anti-inammatory activities by inhibiting nitric oxide (NO). Method : a double blind randomized clinical trial was conducted in Adam Malik Hospital in september-november 2017. OA patients were assessed for WOMAC score and screened for liver and renal function before given treatment. They were randomized to receive combination of Sidaguri extract and meloxicam or meloxicam and placebo in a double-blind technique. Each group involved 25 patients who received one month therapy. At the end of therapy, all patients were rechecked their liver and renal function, and also reassessed the WOMAC score. Data were statisctically analyzed. Result : After one month therapy, we redid the WOMAC assessment to all the patients . The total score of WOMAC after given Sidagurimeloxicam is 7,2 (3,12-17,7)%, while the meloxicam-placebo is 36,4(22-71,8)% (p=0,0001). Conclusion : Sidaguri extract can be given as an effective alternative therapy in osteoarthritis patients.
Authors and Affiliations
Indah Permata Sari, Blondina Marpaung
Keywords
Related Articles
- EP ID EP549535
- DOI -
- Views 161
- Downloads 0
Experimental Investigation of Waste Foundry Sand on Strength Properties of Plain Concrete and Comparison With Binary Blended Concrete
An acute shortage of river sand which is generally used as a fine aggregate in concrete has been affecting the construction sector. The scarcity has led to the skyrocketing price of sand, escalating construction costs. T...
WORKING CAPITAL MANAGEMENT IN AMARA RAJA BATTERIES LIMITED, CHITTOOR DISTRICT, ANDHRA PRADESH
The battery is one of the most important man made inventions all throughout history. Today, it is generally used as a portable source of power. Batteries are classified by chemistry and the most common are lead, lithium...
Investigations in Osteoarthitis
Osteoarthritis (OA) also known as degenerative arthritis, degenerative joint disease and osteoarthrosis, is a group of mechanical abnormalities involving degradation of joints, including articular cartilage and subchondr...
PERCEPTION OF PASSIONATE TEACHERS –THE MOTIVATOR OF FUTURE CLASSROOM LEARNING
The present era mostly concentrates and enforces the need and essential use of ethics in all areas right from teaching. Education is a fundamental process of human life. Teachers are the motivators of students in inspiri...
INFORMATION AND COMMUNICATION TECHNOLOGY IN TEACHING, LEARNING AND EVALUATION.
Information and communication technology have affected every aspect of human activity and have a potential role to play in the eld of teaching, learning and evaluation. The purpose of this paper is to review the uses of...