EFFECT OF STABILIZERS ON THE CHEMICAL AND PHOTODEGRADATION OF ASCORBIC ACID IN AQUEOUS SOLUTION
Journal Title: Baqai Journal of Health Sciences - Year 2016, Vol 19, Issue 1
Abstract
Ascorbic acid (vitamin C) is susceptible to light and air and forms various degradation products. A number of stabilizers have been used to study their effect on the degradation of ascorbic acid (AH2) in dark and light at pH 4.0 and 6.0 alone and in combination with citric and tartaric acids. The assay of AH2 in degraded solutions was performed by a specific UV spectrometric method. The degradation product of AH2 at pH 4.0 and 6.0 was identified as dehydroascorbic acid. The degradation of AH2 has been found to follow first-order kinetics. The apparent first-order rate constants, t90 and percent inhibition in rate in the presence of stabilizers and the second-order rate constants for the interaction of stabilizers with AH2 have been determined. The highest stabilizing effect on AH2 was found by sodium metabisulfite, followed by sodium sulfite, sodium bisulfate, sodium thiosulfate and thiourea. The pH of the solutions has also been found to influence the degradation of AH2 as the rates are higher at pH 6.0 compared to those of pH 4.0, probably due to the ionization of AH2. A synergistic effect has been observed when citric or tartaric acid was added to the solutions containing stabilizers where citric acid showed comparatively better effect.
Authors and Affiliations
Iqbal Ahmad, Zufi Shad, Kiran Qadeer, Raheela Bano
Keywords
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