Effect of supplemental pre-operative fluid on postoperative nausea and vomiting among patients undergoing laparoscopic cholecystectomy
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Postoperative nausea and vomiting continues to be a common and distressing complication of surgery. The purpose of this study was to determine the effect of preoperative volume loading with Ringer lactate solution on the incidence of PONV after laparoscopic cholecystectomy. Materials and methods: Among sixty patients, aged 18-65 years, scheduled to undergo elective laparoscopic cholecystectomy were randomized into two groups. Group A received intravenous ringer lactate of 2ml/kg/hr, whereas Group B received intravenous ringer lactate of 12ml/kg/hr. Rest of the anaesthesia protocol was similar in both groups. Parameters compared included intraoperative hemodynamics, incidence of postoperative nausea and vomiting during 0-5 hours and 6-24 hours in the postoperative period. Results:There was a significant reduction in the SBP in the Group A compared to the Group B after induction of anaesthesia. The drop in the mean SBP was 16% in Group A compared with 10.01% drop in the Group B on induction of anaesthesia.In the 0-5 interval the number of patients experienced no nausea and no vomiting in Group A were 6(20%) and in Group B were 16(53%). There was a statistical significant difference between the two groups. In the 0-5hrs the incidence of nausea was 33% in Group A and 30% in Group B and the incidence of vomiting was 47% and 16% in Group A and Group B respectively. In the 5-24 interval the number of patients experienced no nausea and no vomiting in Group A were 8(27%) and in Group B were 20(67%). There was a statistical significant difference between the two groups. In the 5-24hrs the incidence of nausea was 40% in Group A and 23% in Group B and the incidence of vomiting was 13% and 0% in Group A and Group B respectively. The incidence of rescue antiemetic in the 0- 5hrs in Group A was 47% and Group B was 17% and in the 6-24 hrs in Group A was 47% and Group B was 17%. There was statistical difference between the groups p (<0.05). Conclusion:The postoperative nausea and vomiting can be reduced by the use of preoperative supplement of ringer lactate solution, which is a safe, cheap and cost effective therapy.
Authors and Affiliations
Ramesh V, L. Chaoba Singh, ,S. Sarat Singh3 ,, N. Ratan Singh4, Larinmawia Ralte5, Praneshwori Sinam6, Manglembi P. Chanu7
Keywords
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- EP ID EP365246
- DOI 10.9790/0853-1702145864
- Views 56
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