Effect of Systemic Administration of Curcumin on Ischemia-Reperfusion Injury in Ovaries: An Animal Model Study
Journal Title: Iranian Journal of Veterinary Surgery - Year 2019, Vol 14, Issue 1
Abstract
Objective- Ovarian torsion must be diagnosed and treated as much early as possible. The aim of the present study was to investigate effects of intraperitoneal administration of curcumin on ischemia-reperfusion injury in ovaries. Design- Experimental Study. Animals- Twenty-four healthy female Wistar rats. Procedures- Twenty-four healthy female Wistar rats weighing approximately 260g were randomized into four experimental groups (n = 6): Group Sham: The rats underwent only laparotomy. Group I: A 3- hour ischemia only. Group I/R: A 3-hour ischemia and a 3-hour reperfusion. Group I/R/C: A 3-hour ischemia, a 3-hour reperfusion and 1 mg/kg intraperitoneal administration of curcumin 2.5 hours after induction of ischemia. Results- Curcumin treated animals showed significantly ameliorated development of ischemia and reperfusion tissue injury compared to those of other groups (p<0.05). The significant higher values of SOD, GPO and GST were observed in I/R/C animals compared to those of other groups (p<0.05). The damage indicators (MDA) was significantly lower in I/R/C animal compared to those of other groups (p<0.05). Conclusion and clinical relevance- Intraperitoneal administration of curcumin could be helpful in minimizing ischemia-reperfusion injury in ovarian tissue exposed to ischemia.
Evaluation of Ultrasonography and Mammography in Diagnosis of Mammary Gland Tumor in Bitches: Based on Tumor Markers
Objective- This study refers to the role of ultrasonography in the diagnosis of mammary gland tumor in bitches as a complementary diagnostic method and its ultimate goal is to evaluate the results of mammography with the...
Histopathological and Serum Enzyme Changes of Propofol Combined with Pre-Anesthetic Agents in Domestic Pigeons (Columba livia)
Objective- Because of the several differences between avian and mammalian physiology and anatomy, avian anesthesia requires to be more attentive. The aim of this study was to determine a safe injectable anesthetic agent...
Evaluation of Mastitis Impact on Lameness and Digital Lesions in Dairy Cows
Objective: This current study was done to find any correlation between clinical mastitis and lameness occurrence and incidence in dairy farms. Design: This prospective field trial was done on a case control study basis....
Ocular Ultrasonographic Features in Iranian Native Donkey
Objective- The aim of this study was to evaluate ultrasonographic appearance of the normal eye and obtaining reference values of ocular structures in Iranian native donkey. Design- Experimental study. Animals- Five Irani...
Ultrasonographic Assessment of Caudal Vena Cava to Aorta Ratio as a Novel Endpoint in Hemorrhagic Shock Resuscitation in Dogs
Objective- The aim of this study was to assess ultrasonography-derived caudal vena cava to aorta ratio (CVC/Ao) as a novel endpoint in the resuscitation of experimental hemorrhagic shock in dogs. Design- Experimental stu...