Effect of telmisartan on blood glucose levels in euglycemic albino rats
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 2
Abstract
Introduction Diabetes is considered primary risk factor for heart disease and comorbidities in older people and in children Due to escalating epidemic diabetes is concerned high profile public health problemMaterials and Methods Swiss albino rats weighing around 150200gms of either sex were randomly selected from the central animal facility Animals were randomly divided into 2 groups six animals in each group A group of 3 rats were kept in individual cages The control was given 05 ml 1 Gum acacia test group was given Telmisartan at the dose of 72mgkgday All the drugs were given orally and for the period of 5 days All rats were fasted overnight before the 5th day On the 5th day glucose 06gmkg body weight was given orally using oral feeding tube and oral glucose tolerance test OGTT was performed Blood was collected by tail snipping method and capillary blood glucose was assessed at 0 60 and 150 minutes using a glucometerResults Fall in capillary blood glucose level was seen in Telmisartan group at alltime intervals when compared to control groupConclusionTelmisartan when given orally for 5 days showed fall in blood glucose level in swiss albino rats Keywords Adipokines Capillary blood glucose Diabetes Euglycemic
Authors and Affiliations
Siddamma Amoghimath, Mrutyunjay Mirje
Keywords
Related Articles
- EP ID EP478544
- DOI 10.18231/2393-9087.2018.0015
- Views 86
- Downloads 0
Assessment of health related quality of life of drug resistant tuberculosis patients
Objectives Assessment of Health Related Quality of Life HRQoL of drug resistant tuberculosis patients at the start of treatment under PMDT regimeMaterials and Methods This observational study was conducted on a cohort of...
Efficacy of wound infiltration with ropivacaine, lornoxicam or their combination in total abdominal hysterectomy
Wound infiltration with local anaesthetics with or without adjuvant is an alternative and acceptable method for the management of postoperative pain. In this study wound infiltration with two newer drugs ropivacaine and...
Retrospective analysis on adverse drug reactions prevalence in the female population of Tertiary Care Hospital
Introduction Adverse drug reactions seems to be a major problem in women than menObjective This study as planned to assess the incidence rate clinical manifestations and causative agents for adverse drug reactions ADRs i...
Evaluation of Efficacy of Nevirapine Regimen versus Efavirenz Regimen
Introduction: CD4 count can be used as marker to assess the effectiveness of antiretro viral treatment (ART), mortality and survival rates in HIV patients. It is an important guide to treatment as it reflects drug resist...
Assessment and analysis of adverse drug reactions in outpatient department of mental hospital of a tertiary care teaching institute of central India
Objective: To monitor and analyze the adverse drug reactions (ADRs) in outpatient department of mental hospital of a tertiary care teaching institute of central India. To assess the causality between drug and adverse rea...