Effect of the addition of the antioxidant taurine on the complete blood count of whole blood stored at room temperature and at 4°C for up to 3 days
Journal Title: The International Journal of Frontier Sciences - Year 2017, Vol 1, Issue 1
Abstract
Background: The complete blood count is one of the most common routine tests. This study aimed to evaluate possible effects of the antioxidant taurine on the complete blood count of whole blood stored at room temperature and at 4°C over three days. Methods: Venous blood samples of 15 healthy males were distributed into two sets of tubes with each set of three tubes containing 50 μL of solutions with zero, 5 g/L, 10 g/L taurine. The tubes were kept at room temperature or at 4°C. Complete blood counts were performed on three successive days. The mean percentage changes [Δ = (mean value – mean baseline value) / mean baseline value x 100] were calculated and compared. Results: Complete blood count parameters exhibited different patterns of behaviour which were affected by the storage temperature, time and taurine concentration. Taurine at room temperature significantly enhanced the stability of: the platelet count over three days (Δ3 at 5 and 10 g/L taurine were 6.18, and 2.53 x 109 cells/L, respectively); the red blood cell count over three days (Δ3 at 5 and 10 g/L taurine were 2.59, and 1.39 x 1012 cells/L, respectively); mean corpuscular haemoglobin over three days (Δ3 at 5 and 10 g/L taurine were,-0.62 and -0.52 fl respectively); and red cell distribution width over two days (Δ2 at 5 and 10 g/L taurine were 1.30% and -0.1%, respectively). No additional stabilizing effects of taurine were reported for the mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, haematocrit and haemoglobin, while it negatively affected the white blood cell stability. Conclusion: Complete blood count parameters exhibited variable stability patterns in respect to temperature, time and taurine concentration.
Authors and Affiliations
Muhammad Abdul Ghaffar, Muhammad Asif Naveed, Rehma Dar
Keywords
Related Articles
- EP ID EP48978
- DOI -
- Views 376
- Downloads 0
Frequency of Parenteral Exposure and Seroprevalence of HBV, HCV and HIV among Operating Room Personnel
Background: There are many experiences in the operation theatre professionals to get Hepatitis B virus, Hepatitis C virus and Human immunodeficiency virus during their profession in operating room due to accidental needl...
Frequency of Infection in Cervical Lymph Node Biopsy Site using Chlorhexidine and Povidine Iodine
Background: Lymph node are located throughout the lymphatic system, they are concentrated in certain areas of the body including head and neck. Cervical lymph nodes are lymph nodes found in the neck. Of the 800 lymph n...
Reforms Needed in Aged Patient’s Care
Today’s health workforce is constantly engaged to enhance the standards of healthcare services and ensuring comprehensive healthcare standards to the community. Queensland’s health workforce is Australia’s second largest...
Post-Operative Pain Comparison between Peri-Operative Bupivacaine Infiltration Vs Post-Operative Opioids Analgesics in Patient Undergoing Abdominal Surgery in First 6 Hours
Background: To compare between opioids and wound infiltration to reduce post-operative pain in abdominal surgery in first 6 hours, in appropriate treatment, contraindications of treatment and increase mortality of pati...
Knowledge, Attitude and Practice in Diabetic Patients About Diabetic Foot Disease
Background: Diabetic foot disease (DFD) is a major challenge for the healthcare system, with enormous economic consequences for people living with diabetes, their families and society and it affects both quality of lif...