“Effectiveness of Radiation Sterilized Amniotic Membrane in Reducing Patient’s Morbidity In Comparison To Non Biological Dressing Like Medicated Tulle (Sofra Tulle)”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
This study was performed to observe whether local burn wound coverage with radiation sterilized amniotic membrane provides a better outcome than conventional dressings with non biological medicated tulle (sofratulle).This interventional randomized control trial study was conducted during the period of 15 months from 01, July, 2006 to 30, September, 2007 in Burn Unit of Dhaka Shishu(Children) Hospital. 50 burned patients with 10- 20% of total body surface area and suffering from second degree superficial burn(scald) were allocated randomly into two groups, the first receiving classical dressings with sofratulle, and the second had the burn areas covered with radiation sterilized amniotic membrane dressing. Each patient in both groups received a same standard schedule of general management. Patients were followed up on daily basis for number of dressing changes, development of pyrexia, wound infection, and wound healing time, duration of hospital stay and requirement of further surgical procedures like skin grafting. After recovery, the patients were followed up on weekly basis for up to 4 weeks and on monthly basis for up to two months thereafter. Any signs of abnormal scar formation, wound contracture and cosmetic disfiguration were recorded. In present study wounds of 7(28%) patient healed up in 14 days and 18(72%) patients required 15 days or more to heal up their wounds in group A (sofratulle).On the other hand wound healed up in 22 (88%) patient in 14 days and in 3(12%) patients required 15 days or more to heal up their wounds in group B (amniotic membrane).So amniotic membrane group demonstrated a clear early wound healing rate. Hospital stay was also significantly short in amniotic membrane group. Present study revealed that only 1 patient in medicated tulle (sofratulle) group required single dressing and rest 24 patients required multiple dressings. While 17 patients in amniotic membrane group required single dressing and rest 8 patients required multiple dressings. Out of 25 patients in medicated tulle (sofratulle) group 8 showed positive culture of pathogenic organisms with pyrexia and neutrophilia with an infection rate of 32%.In amniotic membrane group one patient had positive culture of pathogenic organisms with pyrexia and neutrophilia, making an infection rate of 4%. In the present study 100% patients of amniotic membrane group required no further procedure for wound healing but 2(8%) patients in medicated tulle (sofratulle) group required skin grafting. The present study demonstrated that amniotic membrane is a suitable and effective biological dressing in reducing patient’s morbidity when compared with non-biological medicated tulle (sofratulle).
Authors and Affiliations
Dr. Shah Md. Ahsan Shahid, Professor AR Khan, Dr. Md. Mostafizur Rahman, Dr. Khondokar Seheli Nasrin Lina
Keywords
Related Articles
- EP ID EP452654
- DOI 10.9790/0853-1801185154.
- Views 40
- Downloads 0
A Comparative Study of Aspiration Vs Non Aspiration Technique in Fine Needle Cytology of Thyroid Lesion
Background: Fine‑needle aspiration (FNA) of thyroid gland is a widely accepted, simple, safe and accurate method for evaluation of thyroid lesion. Fine needle non-aspiration/ Fine needle capillary cytology (FNNAC/FNC) is...
Bone Marrow Involvement in Non Hematological Disorders – An Institutional Experienc
Objective: To find out the frequency of involvement of bone marrow by non – haematological disorders in our institution and to evaluate the role of bone marrow aspiration and biopsy in diagnosing these disorders. Materia...
The Role of Umbilical Artery Doppler Velocimetry in Oligohydramnios ator Beyond 34 Weeks and Its Correlation withFetal Outcome
Amniotic fluid volume measurement forms an integral part of antenatal fetal monitoring in routine obstetric scans. Oligohydramnios has been identified as the leading cause of increased perinatal morbidity and mortality....
Physiological Parameters Related To Anxiety In Dental Surgery
The anxiety is an emotional state that cannot be controlled by the consciousness, thus it causes many symptoms which can interfere on dental care. This work reviews the anxiety concepts and evaluates the physiological pa...
Clinical And Audiological Assessment of Patients Undergoing Various Types of Tympanomastoid Surgeries
Objective: To assess the hearing improvement and healing in the patients who have undergone various Tympanomastoid surgeries for different causes basing on the recording of the pure tone audiometry. Setting: Study was co...