Effectiveness of the different methods of inhalation drugs delivery in children with bronchial asthma

Journal Title: Здоров`я дитини - Year 2017, Vol 12, Issue 1

Abstract

Aim of the work — to evaluate the effectiveness of inhalation technique when using different types of inhalers (dry powder inhalers — Turbuhaler, Diskus), metered-dose inhalers, breath-actuated inhalers — Easyhaler). Materials and methods. 45 patients aged 6–17 years underwent the evaluation of inhalation technique accuracy with the use of In-Check-Dial — apparatus, which imitates the airway resistance that should be overcome during inspiration through different inhaler types, and measure inspiration velocity. Incidence of mistakes was studied in different age groups. Results. 80 % of children aged 6–7 years made mistakes while using Turbuhaler, 73.3 % — metered-dose inhaler, 60 % — Easyhaler. There were no mistakes in patients making inhalation by means of Diskhaler. 100 % of children aged 12–14 years incorrectly used metered-dose inhaler. Easyhaler was incorrectly used in 66.6 % of cases, Diskhaler — in 26.6 %. Among elder group, incidence of mistakes when making inhalations through Turbuhaler was lower — 40 % in 12–14-year-old group and 25 % — in 15–17-year-old (р < 0.05). Children of 15–17 years old are able to use Turbuhaler and Diskus (mistakes in 33.3 and 46.6 %, respectively). At the same time, none of the patients have done the correct inhalation by means of metered-dose inhaler, 93.3 % of the patients have mistakes when using Easyhaler. Conclusions. The incidence of mistakes depends on the age and inhaler type and reaches 26–100 %. Minimal quantity of mistakes is seen for Diskus (in all age groups), maxi­mal — for metered-dose inhaler. For the purpose of optimal inhaler choice in a child with bronchial asthma, it is advisable to measure the inspiratory flow with the help of In-Check-Dial before therapy administration.

Authors and Affiliations

S. M. Nedelska, O. D. Kuznietsova, N. M. Taran, A. Aleschenko

Keywords

Related Articles

Molecular-genetic concept of the formation of psychological type in children with obesity associated with lactose intolerance

Background. The purpose of the study was to determine the association of single-nucleotide polymorphisms (SNP) in the lactase gene (LCT) with the development of obesity in children based on the study of personal and reac...

The Spectrum of Sensitization in Infants with IgE-Dependent Mechanism of Disease in a Large Industrial Area

Recently, the role of anthropogenic impact on the human bodysignificantly increased, which determines the spread of allergic pathologies in children. Among 318 infants with IgE-dependent skin diseases maximum level of hy...

Immunologic Reactivity in Adolescents with Duodenal Ulcer

The article presents the results of studying immunological and cytokine status in adolescents with duodenal ulcer. Duodenal ulcer is associated with increased levels of interleukin (IL)-1β, IL-4, IL-6 and the decrease in...

Well-Forgotten Old

The article presents a case report of severe sepsis in weakened child with immunodeficiency. A week of intensive treatment was not able to stop the process. Attempts to force the body to fight infection itself by fresh f...

The Antioxidant System of the Respiratory Tract. The Intracellular Antioxidant Protection in the Respiratory Tract (Part 2)

The literature review presents the current data about the enzyme of intracellular antioxidant protection in the respiratory tract — catalase. The characteristics of catalase is presented and its functioning is described....

Download PDF file
  • EP ID EP180068
  • DOI 10.22141/2224-0551.12.1.2017.95017
  • Views 114
  • Downloads 0

How To Cite

S. M. Nedelska, O. D. Kuznietsova, N. M. Taran, A. Aleschenko (2017). Effectiveness of the different methods of inhalation drugs delivery in children with bronchial asthma. Здоров`я дитини, 12(1), 13-17. https://europub.co.uk/articles/-A-180068