Effectiveness of topiramate in lipomatosis comorbid with agoraphobia and migraine. Case study
Journal Title: Archives of Psychiatry and Psychotherapy - Year 2015, Vol 17, Issue 1
Abstract
Topiramate has been used in epilepsy and migraine for more than ten years. Recently, it has gainedimportance in the treatment of obesity, particularly in combination with phentermine. We report thecase of a 51-year-old woman suffering from agoraphobia with panic attacks, diabetes and migraine.In addition, she simultaneously developed generalized lipomatosis leading to a weight gain of morethan 20[th]kg. She was given topiramate up to 100[th]mg per day in addition to an SSRI (citalopram)and a melatoninergic drug (agomelatine). Gradually, within two years after starting topiramate, shelost 20[th]kg, with a corresponding reduction of thorax and arm circumference. Although the mechanismof weight loss remains to be clarified, topiramate may be an alternative approach in patientssuffering from generalized lipomatosis.
Authors and Affiliations
Josef Koch
Keywords
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- EP ID EP153616
- DOI 10.12740/APP/34715
- Views 71
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