EFFECTIVENESS OF TWO PHYSICAL ACTIVITY PROGRAMS ON NON-ALCOHOLIC FATTY LIVER DISEASE. A RANDOMIZED CONTROLLED CLINICAL TRIAL.
Journal Title: INTERNATIONAL JOURNAL OF PURE MEDICAL RESEARCH - Year 2018, Vol 3, Issue 8
Abstract
BACKGROUND & AIMS: Several studies have shown that lifestyle modication (reduced energy intake and/or increased physical activity) reduces Non-Alcoholic Fatty Liver Disease (NAFLD). We hypothesized that Aerobic exercise is more efficient to reduce NAFLD score in a primary care setting. Primary aim of this study was to estimate the effectiveness of two physical activity programs on NAFLD METHODS: Participants come from a survey conducted in the Apulian region of Italy. Subject with moderate or severe NAFLD were invited to participate. After informed consent, they completed a questionnaire, underwent ultrasonography and anthropometric measurements. Thus, they were randomized: Aerobic or Combined Exercise programs and followed-up for six months. Adherence to the intervention was measured. A mixed linear model was applied to the data. RESULTS: Adherence to Aerobic Exercise was homogeneous and increased with time. Combined Program adherence was equal to 100% in every month for all subjects. There was no signicant difference in NAFLD mean score by treatment at baseline (p=0.22) and after six months (p=0.65). However, there was a signicant reduction in NAFLD mean score for treatments after six months (p< 0.01). The NAFLD measured score was reduced, on average, 22% in the Aerobic treatment group. CONCLUSIONS: Combined program after 6 months was less or not as effective as Aerobic Exercise in reducing NAFLD score. This nding is relevant as Aerobic exercise programs are simple to implement and the cost-effectiveness is higher. Moreover, Aerobic exercise program is a realistic intervention which could be part of primary prevention of several chronic diseases.
Authors and Affiliations
Isabella Franco, Antonella Bianco, María del Pilar Díaz, Caterina Bon, Marisa Chiloiro, Sonia A Pou, Julia Becaria Coquet, Alessandro Nitti, Angelo Campanella, Maria G Caruso, Mario Correale, Alberto R Osella
Keywords
Related Articles
- EP ID EP598570
- DOI -
- Views 32
- Downloads 0
THE CLINICAL USE OF THE URINARY G1 CELL CYCLE ARREST BIOMARKER { TIMP-2} FOR EARLY PREDICTION OF ACUTE KIDNEY INJURY IN CRITICALLY ILL CHILDREN
BACKGROUND: Acute kidney injury (AKI) is a serious complication, commonly occurring in the critically ill population, with devastating short- and long-term consequences , and its incidence is rising at an alarming rate ....
POSTOBSTRUCTIVE NEGATIVE PRESSURE PULMONARY EDEMA
Acute pulmonary negative pressure edema (NPPE) also known as post-obstructive pulmonary edema is a life-threatening clinical scenario in which pulmonary edema develops immediately after upper airway obstruction. A review...
PATTERN OF SIGMOID COLON VOLVULUS IN ABDOMINAL SUPINE RADIOGRAPHY
Introduction: In Asia, Africa, and less-developed regions, Volvulus of the sigmoid colon can account for 20 to 50% of intestinal obstruction. Classic ndings on radiology include the “bent inner tube” or “coffee bean” si...
AWARENESS AND ACCEPTANCE OF HUMAN PAPILLOMAVIRUS (HPV) VACCINE: A STUDY AMONG FEMALE UNDERGRADUATES AND ANTENATAL MOTHERS IN PORT HARCOURT, NIGERIA.
There has been no reported study on the awareness and acceptability of Human Papilloma Virus (HPV) vaccination among female University students and antenatal mothers in Port Harcourt. HPV has been implicated as the highe...
THE EFFECTS OF DRUG ABUSE ON YOUTH PRODUCTIVITY IN CALABAR OF CROSS RIVER STATE
In the last two decades there has been so much attention from both international and local organisations on substance and drug abuse by youths in many parts of the world including Nigeria. Despite this focus and preventa...