EFFECTIVENESS OF VAGINAL VERSUS BUCCAL MISOPROSTOL FOR FIRST TRIMESTER INDUCED ABORTIONS- A COMPARATIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 59
Abstract
BACKGROUND Abortion can be induced by medical or surgical methods, of which medical abortion is safer, including misoprostol, administered by various routes. Vaginal administration, although effective, may require repeated vaginal examinations, being inconvenient and unacceptable at times. This has paved way for other routes of misoprostol administration such as buccal and sublingual, with additional benefits including ease of administration and lesser infection rate. Objectives- To compare the safety, effectiveness and patient satisfaction of vaginal and buccal misoprostol in first trimester induced abortion. MATERIALS AND METHODS A prospective randomised study in hundred women undergoing first trimester induced abortion up to 49 days were divided into two groups. Group A, with 50 patients, were given oral mifepristone (200 mg) followed by vaginal misoprostol (800 mcg). Group B, with 50 patients, were given oral mifepristone (200 mg) followed by buccal misoprostol (800 mcg). Results were compared in both the groups in term of safety, effectiveness and patient satisfaction. RESULTS In both the groups, first trimester induced abortions up to 49 days (7 weeks) were safe. The efficacy as judged by complete abortion was 88% in group A (vaginal) and was 94% in group B (buccal). No statistical significant difference in safety and complete abortion was observed. Statistical significant adverse effects noticed was altered taste in group B (buccal). No statistical significant difference in patient satisfaction in both groups was observed. CONCLUSION Vaginal and buccal misoprostol have similar efficacy and patient satisfaction. For first trimester induced abortion, buccal route can be used as an effective alternative.
Authors and Affiliations
Zareena Hassan Khan, Sameena Akhter, Shashi Gupta
Keywords
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- EP ID EP226333
- DOI 10.14260/Jemds/2017/943
- Views 93
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