Effects of Achyranthes aspera to the Immunity of Rohu (Labeo rohita) against Pseudomonas fluorescens
Journal Title: Journal of Pharmaceutical Research International - Year 2016, Vol 12, Issue 5
Abstract
Aims: The present study evaluated the efficacy of Achyranthes aspera extract on immunological parameters and disease resistance against Pseudomonas fluorescens infection in Indian major carp, Rohu, Labeo rohita. Study Design: One hundred and eighty (180) fish with average weight (28.1±1.2 g) were acclimatized and stocked in (6) indoor aquariums (100 L) for three days. Place and Duration of Study: This experiment was performed in the Laboratory of Fisheries and Marine Bioscience (FMB) and Department of Microbiology, Jessore University of Science and Technology (JUST), on November to April 2014-2015. Methodology: Fish and management, A. aspera extract preparation, herbal diet preparation with four (4) different doses 0%, 2%, 4% and 6% of A. aspera extract, nonspecific immune response assay, blood and serum collection for hematology and immunology, phagocytic activity and challenges test were performed. Results: Among the entire dose the 6% doses of A. aspera showed highest significant responses in phagocytic activity, specific and non-specific immune responses on week 4 compared to control diet whereas the changes did not manifest on first week. Further the A. aspera enriched diet at 6% level resulted in lowest mortality (20%) indicating highest protection (relative percent survival 80%) from Pseudomonas fluorescens infection than 0%, 2% and 4% doses t that resulted 73.33%, 46.67% and 33.33% mortalities respectively. Conclusion: The results are suggested that the dietary supplementation of Achyranthes aspera extract acts as immunostimulants, reduce mortality and increase disease resistance in Labeo rohita against Pseudomonas fluorescens infection.
Authors and Affiliations
Md. Hasan-Uj-Jaman, Md. Mer Mosharraf Hossain, Shoumo Khondoker, Md. Eftakher Alam, Md. Farid Uz Zaman, Sanjoy Banerjee Bappa
Keywords
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- EP ID EP342138
- DOI 10.9734/BJPR/2016/28110
- Views 118
- Downloads 0
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