Effects of age on visual evoked potentials
Journal Title: Medpulse International Journal of Physiology - Year 2018, Vol 6, Issue 1
Abstract
Background: Pattern-reversal visual evoked potential (PRVEP) is an objective, sensitive and non-invasive neurophysiological test that can prove to be a useful clinical tool in investigating the physiology and pathophysiology of human visual system. But results of PRVEP are affected by different physiological parameters like age, gender, head size, BMI. The present study was undertaken to find out the effect of age on pattern –reversal visual evoked potential (PRVEP). Materials and Methods: PRVEP was recorded in 60 healthy volunteers in the age-group of 18-75 years. They were divided into 2 age groups below and above 40 yrs. Mean P100 latencies and N75-P100 amplitudes were compared in 2 groups Result: The present study demonstrated that mean P100 latency is significantly prolonged in older subjects (p<0.001) while mean N75-P100 amplitude is significantly reduced. Conclusion: Prolonged PRVEP P100 latency with age reflects electrophysiological alterations in visual pathways. PRVEPs are useful objective measures to investigate the involvement of neural elements of visual system in the elderly individuals.
Authors and Affiliations
Kiran Narayan Avachar, Avantika Kisanrao Kayapak, Milind Sharad Chitale
Keywords
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