Effects of Aloe Vera and Chitosan Nanoparticle Thin-Film Membranes on Wound Healing in Full Thickness Infected Wounds with Methicillin Resistant Staphylococcus Aureus
Journal Title: Bulletin of Emergency And Trauma - Year 2018, Vol 6, Issue 1
Abstract
Objective : To assess effect of Aleo vera with chitosan nanoparticle biofilm on wound healing in full thickness infected wounds with antibiotic resistant gram positive bacteria. Method: Thirty rats were randomized into five groups of six rats each. Group I: Animals with uninfected wounds treated with 0.9% saline solution. Group II: Animals with infected wounds treated with saline. Group III: Animals with infected wounds were dressed with chitosan nanoparticle thin-film membranes. Group IV: Animals with infected wounds were treated topically with Aloe vera and Group V: Animals with infected wounds were treated topically with Aloe vera and dressed with chitosan nanoparticle thin-film membranes. Wound size was measured on 6, 9, 12, 15, 18 and 21days after surgery. Results: Microbiology, reduction in wound area and hydroxyproline contents indicated that there was significant difference (p<0.05) between group V and other groups. Quantitative histological studies and mean rank of the qualitative studies demonstrated that there was significant difference (p<0.05) between group V and other groups. Conclusion: The Aloe vera with chitosan nanoparticle thin-film membranes had a reproducible wound healing potential and hereby justified its use in practice.
Authors and Affiliations
Reza Ranjbar, Alireza Yousefi
Keywords
Related Articles
- EP ID EP305390
- DOI 10.29252/beat-060102
- Views 68
- Downloads 0
Characteristics of Occupational Injuries in a Pharmaceutical Company in Iran
Objective: To prioritize occupational hazards in a Pharmaceutical Company in Iran using the analytical hierarchy process (AHP). Methods: This was a cross-sectional study conducted in a Pharmaceutical Company in Iran in 2...
Otolaryngological Presentations in Times of Terror: Profile from a Tertiary Health Center in North-Central Nigeria
Objectives: To report the incidence, socio-demographic characteristics, otorhinolaryngological presentations and outcomes of management of patients at the Jos University Teaching Hospital following terror attacks. Method...
Epidemiology and Pattern of Traumatic Brain Injury in a Developing Country Regional Trauma Center
Objective: To determine the epidemiological aspects of patients with traumatic brain injury (TBI) in a regional trauma center. Methods: A cross-sectional study was conducted on patients with TBI during 2013 to 2016 in a...
Descriptive Analysis of Right and Left-sided Traumatic Diaphragmatic Injuries; Case Series from a Single Institution
Objective: To investigate the presentation, management and outcomes of left and right-sided traumatic diaphragmatic injury (TDI) in a single level I trauma center. Methods: This cross-sectional study was conducted during...
A Questionnaire Study on the Attitudes and Previous Experience of Croatian Family Physicians toward their Preparedness for Disaster Management
Objective: To explore family physicians’ attitudes, previous experience and self-assessed preparedness to respond or to assist in mass casualty incidents in Croatia. Methods: The cross-sectional survey was carried out du...