Effects of aqueous crude leaf extract of senecio biafrae on the histology of the frontal cortex, kidney, liver and testis of male sprague dawley rats
Journal Title: Scientific Journal of Biological Sciences - Year 2012, Vol 1, Issue 1
Abstract
Whenever any plant and/or herb is ingested, the body system interacts with it in an attempt to get rid of any harmful toxins such may contain, especially if the body cannot convert the foreign substance into useful components. This study was to evaluate the effects of oral consumption of aqueous leaf extract of Senecio biafrae on the histology of the frontal cortex, kidney, liver and testis of Sprague Dawley rats as a marker of toxicity. Twenty adult male Sprague Dawley rats weighing between 100-158 g were used (4-6 weeks old). They were divided into 2 groups. The rats in the treatment group A received 300 mg/kg body weight of the aqueous leaf extract of S. biafrae for thirty days (30d). Histological observation of the frontal cortex, liver, kidney and testes revealed no significant abnormal alterations. The rats in the control group B received equal volume of phosphate buffered saline (PBS) also for 30d and no histopathological abnormalities were seen in the frontal cortex, kidney, liver, and testes of the rats. Aqueous leaf extract of S. biafrae has no deleterious effects on the histological profile of the frontal cortex, liver, kidney and testis of the rats.
Authors and Affiliations
A. O. Muhammed| Histopathology Unit, University of Ilorin Teaching Hospital, Ilorin, Nigeria, D. A. Adekomi*| Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Nigeria, and A. A. Tijani| Department of Anatomy, College of Health Sciences, Osun State University, Osogbo, Nigeria
Keywords
Related Articles
- EP ID EP1058
- DOI -
- Views 669
- Downloads 45
Histological study of the effects of oral administration of datura metel on the visual system of male wistar rats
This study was carried out in order to elucidate some of the effects of oral administration of Cannabis sativa on the visual system of male Wistar rats as marker of toxicity using neurohistochemical study. 12 adult male...
Reproductive biology and histological characteristics of female little tunny Euthynnus alletteratus (Rafinesque, 1810) caught on continental shelf of Côte d’Ivoire
Some females little tunny (n=395) caught in gillnets and measuring in size from 35 to 76 cm FL (centimetre Fork Length) were sampled from January to December 2004 to study some biological features (length-weight relation...
Survey for incidence and severity of bacterial blight of cotton caused by Xanthomonas axonopodis pv. malvacearum in different districts of Marathwada region
An extensive roving survey was conducted in different districts of Marathwada region of Maharashtra State to isolate the pathogen associated with the bacterial blight disease of cotton. In all 76 cotton fields were surve...
The effects of Ephedra (Ephedra funereal) and protexin probiotic on some blood parameters in male Japanese quail (Coturnix Japonica)
This experiment was conducted to investigate the effects of feeding Ephedra and protexin on performance and some hematological parameters of male Japanese quail. A total of 240 seven days old quail chicks were divided in...
Adoption of improved millet varieties by farmers in Argungu local government area of Kebbi State
The aim of this investigation was to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old) were randomly...