Effects of Aqueous Ethanolic Leaf Extract of Boscia senegalensis ( PERS) on Liver Function of Wiste r Strain Albino Rats
Journal Title: International Journal of Scientific Research and Management - Year 2014, Vol 2, Issue 4
Abstract
Boscia senegalensis has long been used as food, pesticide and medicine for the elimination of intestinal parasite from camel. The objective of this study was to evaluate the acute and sub acute toxicity (21 days) of Boscia senegalensis on the liver of Wist er strain albino rats of both sexes via the oral route. For the acute toxicity, Boscia senegalensis extract was administered in a dose of 1000mg/K g and 2000mg/Kg/day (n=3) while in the sub acute toxicity test, the following doses were administered; 100mg/K g, 150mgK g, 200mg/K g/day (n=5/group) for 21 consecutive days. In the acute toxicity test, Boscia senegalensis produce some toxic signs with no mortality. During the sub acute treatment with Boscia senegalensis , ALT was significantly high at P<0.001, AST wa s significantly high at P<0.05, while ALP was significantly high at P<0.01. However, Albumin and total protein were not significant at P>0.05. Therefore, the acute and sub acute administration of the aqueous ethanolic extract of Boscia senegalensis produce d a toxic effect on Wister strain rats which is proven statistically to be dose dependent.
Authors and Affiliations
M. A. Geidam
Keywords
Related Articles
- EP ID EP209282
- DOI -
- Views 89
- Downloads 0
Hy drological Analysis and Assessment about the impact of Limes tone Mining on water Pollution in Hial Area , Bolangir district, Odisha, India
80 percent area of Odisha are underlain by hard rock .Therefore Ground water resource is very scarce inmost part of the state. Bolangir district is known as drought prone area .Our study area comes under drought prone zo...
Comparison Of External Beam Radiotherapy Followed By Intra - Luminal Brachytherapy With External Beam Radiotherapy Alone In Locally Advanced Carcinoma Of Esophagus
Aim: The aim was to compare the outcome of intraluminal boost brachytherapy following external beam radi otherapy with external beam radiotherapy alone in locally advanced carcinoma esophagus in terms of toxicity, respon...
ESTABLISHING THE RIGHT OF REFUSAL: PUBLIC SERVICE REFORMS POLICIES AND THE THESIS OF IMPOSITION ON NIGERIA BY EXTERNAL FORCES
paper examined the claim that reform policies in the public service of Nigeria especially during the political dispensation between 1999 and 2007 were impositions of the external forces. It d...
Volunteerism as an Approach to Achieve Success – A Case Study Of Akyutha 2k16
Volunteerism is a term very often used for community service but it also has other meaning like it is a policy or practice of volunteering one’s time or talents for charitable, educational...
Reduction of PAPR in OFDM Signals by using Ele ctromagnetism Optimization A lgorithm
Orthogonal Frequency Division Multiplexing grown to be a trendy modulation process inside impressive tempo wireless communications. It is more advantageo us over remaining technologies, even though it h...