Effects of Aqueous Methanolic Extract of Unripe Carica Papaya Fruit on Midterm Pregnancy in Wistar Albino Rats
Journal Title: Journal of Veterinary Advances - Year 2015, Vol 5, Issue 6
Abstract
This study investigated the effects of aqueous methanolic extract of unripe Carica papaya (AMEUCP) on midterm pregnancy in rats. The unripe papaya fruits were extracted by cold marceration. The abortifacient effect of AMEUCP was studied using mature albino rats (15 females and 8 males). Successfully mated rats were separated and classified into three (3) groups (n=5). Group I (control) received 0.5 ml of distilled water while groups II and III received AMEUCP at 450 and 900 mg/kg respectively from the 10th to 12th day of pregnancy and were closely observed for signs of abortion. They were sacrificed on their 20th day of pregnancy and the viable and non-viable fetuses, adsorbing sites and corpora lutea were counted. Data obtained from the study were subjected to one-way analysis of variance (ANOVA). Variant means were separated using the Duncan’s multiple range test and significance was accepted at p < 0.05. This study demonstrated that oral administration of the extract to successfully mated rats induced abortion and was embryotoxic The mean live foetal number (LFN) and the mean day 20 foetal crown rump length (FCRL) in the AMEUCP treated groups were significantly (p < 0.05) lower than those of the control. Therefore, consumption of unripe papaya fruits and its products by man and animals should be done with caution especially during the breeding season or during pregnancy.
Authors and Affiliations
E. O. Odirichukwu
Keywords
Related Articles
- EP ID EP132586
- DOI -
- Views 88
- Downloads 0
Hazards Exposures of Workers of Animal Related Occupations in Abeokuta Southwestern, Nigeria
A cross-sectional survey was carried out to determine the hazard exposures of workers of animal related occupations in Abeokuta Southwestern, Nigeria. A total of 230 workers consisting of Animal health workers, Veterinar...
A Study of the Potential of Using the Goat Weed (Ageratum Conyzoides) as an Anticoccidia Agent in Chicken
This study investigated the speculation that the goat weed, Ageratum conyzoides, has antiprotozoan activity. Various concentrations of potable water and whole extracts of the leaves of Ageratum conyzoides were administer...
Concurrent Demodex Spp. and Psoroptes Spp. Mite Infestation in an Indigenous Cattle: A Case Report
The present case report describes the concurrent infection of Demodex spp. and Psoroptes spp. mites in an indigenous cattle and its successful therapeutic management using parenteral ivermectin. A cattle with hyperkerati...
Isolation, Identification and Antibiogram Study of Pseudomonas Aeruginosa from Cattle in Bangladesh
This study was aimed to isolate and identify Pseudomonas aeruginosa (P. aeruginosa) and to check the susceptibility of isolated P. aeruginosa against some common usable antibiotics. Two isolates of P. aeruginosa were iso...
Incidence and Treatment of Camel Trypanosomosis (Guffar) in West Omdurman in Sudan
The incidence of camel trypanosomosis (Guffar) caused by Trypanosoma evansi (T.evansi) in Omdurman west plain, western Sudan was surveyed using direct smear, Micro Hematocrit Centrfugation Technique (MHCT) and Card Agglu...