EFFECTS OF ARTIFICIAL SWEETENER(ASPARTAME) ON THE WEIGHT OF IMMUNE ORGANS AND GRANULOCYTES CELLS IN RATS
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 9
Abstract
This study aimed to determine the effect of aspartame on the white blood cells. Used for this study 24 adult male rats and 24 adult female rats, with age of 65-70 day, almost on an average live weight between (185-200) g. The experiment has concentrated on the daily dose, where the animals were randomly divided into two groups, each group contains 12animals females. the first, control groupdosed with 1ml physiologic solution daily, the second group gavage with concentrated aspartame (54 mg/kg/per day). The all groups had their daily dosages through the 75 day, and the experiment continued from October 2015- January 2016. After the dosage’s period has been completed, hematological samples have been taken from the rats to examine the count of neutrophils cells and isolation of spleen, thymus and lymph nodes to estimate the weight of it. The results showed there was significant decrease(P<0.05) in theneutrophil count, however no significant differences in monocyte and eosinophil count among groups, compared with the control group. Also showed that the weights of spleen, thymus and lymph nodes in aspartame treated animals were significantly decreased compared to control animals.
Authors and Affiliations
Ali Nayyef Umayra
Keywords
Related Articles
- EP ID EP672891
- DOI -
- Views 169
- Downloads 0
ASSESSMENT OF SAUDI WOMEN AWARENESS ABOUT PAIN RELIEF AGENTS IN LABOR IN AL-HASA CITY OF SAUDI ARABIA
The awareness and attitudes towards labor pain and labor pain relief agents in women are not clearly known. The physiological nature of the pain in labor makes it an experience most women will want to avoid it; effective...
KNOWLEDGE ATTITUDE AND PERCEPTION OF DIABETES MELLITUS AMONG STUDENTS OF UNIVERSITY OF PORT HARCOURT, RIVERS STATE, SOUTH–SOUTH ZONE NIGERIA
Diabetes mellitus (DM) is a chronic, progressive systemic disease characterized by dysfunction in the metabolism of fats, carbohydrates, and protein resulting from absolute or relative insulin deficiency. Symptoms of dia...
ANTIMICROBIAL ANALYSIS OF POLYHERBAL FORMULATION LINKUS COUGH SYRUP
The Herbal products has widely use throughout the globe since 5,000 years. The objective of this study is to determine the antimicrobial analysis of Polyherbal formulation Linkus cough syrup and its comparison with the o...
POTENTIAL ANTI-DIABETIC MEDICINAL PLANTS IN BANGLADESH: A COMPREHENSIVE REVIEW
Diabetes is one of the utmost causes of mortality and the number of diabetes patients are increasing at an alarming rate worldwide. The medicine available for the treatment of diabetes in the market is not less in number...
PRASINOPHYACEAE EVOLUTIONARY RELICT’S CLASS OF ALGAE
About the 80 percent part of the world is covered by the water, they are with the large oceans and the seas, in them lies the photosynthetic algae, they are preset about the depth of the 160 meters, it depends on the wat...