Effects of Carbegoline and Bromocriptine on Prolactin, Progesterone, Luteinizing and Follicle Stimulating Hormones in Hyperprolactinaemic Infertile Women in Orlu, Nigeria
Journal Title: International Journal of Trend in Scientific Research and Development - Year 2021, Vol 5, Issue 5
Abstract
This was an interventional study which evaluated the effects of bromocriptine and carbegoline on prolactin, progesterone, luteinizing and follicle stimulating hormones in hyperprolactinaemic infertile female subjects in Orlu, South East Nigeria.Hyperprolactinaemic females who were attending Gynaecology Clinic at Imo State University Teaching Hospital IMSUTH Orlu participated in the study. The participants were divided into two groups. Group A 30 hyperprolactinaemic females were administered 1.25mg bromocriptine at night for the first one week 2.5mg at week two then 2.5mg twice daily for eighteen weeks. Group B 30 hyperprolactinaemic females were administered 0.25mg carbegoline twice weekly for eight weeks. Serum prolactin, progesterone, LH and FSH were assayed before and after treatment using enzyme linked immunesorbent assay ELISA kits. The significant difference between the mean values of prolactin, LH, FSH and progesterone, in the pre and post treatment with carbergoline and bromocriptine was determined by paired t test. Independent student t test was used to compare between the two treatments. P value 0.05 was considered as statistically significant. Ajaero, Oluchi Chinwe | Unekwe, Prince Chiazor | Ajaero, Nnaemeka Uchendu "Effects of Carbegoline and Bromocriptine on Prolactin, Progesterone, Luteinizing and Follicle Stimulating Hormones in Hyperprolactinaemic Infertile Women in Orlu, Nigeria" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd45169.pdf Paper URL: https://www.ijtsrd.com/medicine/other/45169/effects-of-carbegoline-and-bromocriptine-on-prolactin-progesterone-luteinizing-and-follicle-stimulating-hormones-in-hyperprolactinaemic-infertile-women-in-orlu-nigeria/ajaero-oluchi-chinwe
Authors and Affiliations
Ajaero, Oluchi Chinwe | Unekwe, Prince Chiazor | Ajaero, Nnaemeka Uchendu
Keywords
Related Articles
- EP ID EP699834
- DOI -
- Views 85
- Downloads 0
Improvement of Regional System of Settlement of Samarkand Region
The article deals with the peculiarities of the demographic situation in the region, studies the population dynamics, average annual growth rates, population density, natural and mechanical movement of the population, la...
Design and Fabrication of a Convertor Ladle and Treatment Chamber
The main purpose of this project is to design and fabricate a Convertor Ladle and a Chamber for the treatment of SG Iron that can eliminate the major disadvantages found in the Ladle that is currently being used. To redu...
Internal Migration for Education Challenges Faced by Young Students Migrated to Delhi NCR
Introduction Migration is a well known phenomenon of movement of peoples from one place to another, in India migration of people occurs on a large scale, and there are various reasons of migration, education being one of...
Compressive Strength of Concrete with Partial Replacement of Cement by Fly Ash
During last few decades several researches have been carried out on blending of the fly ash in Ordinary pozzolanic cement OPC . In the present study fly ash is used in Portland pozzolanic material PPC concrete as partial...
Development of Formative Evaluation in the Teaching Learning Process
The process of improving Uzbekistan higher education is based on the need to train a type of professional capable of responding to the demands of social demands with a solid theoretical and practical training. When a dia...