Effects of chlorpheniramine (histamine H1 receptor antagonist) on food and water intake in broiler chickens in hunger and satiety
Journal Title: International journal of Advanced Biological and Biomedical Research - Year 2014, Vol 2, Issue 2
Abstract
The role of histamine in the regulation of food and water intake in mammals and birds of the review, this study evaluated the effects of intraperitoneal administration of chlorpheniramine as histamine H1-receptor antagonist, in broiler chicks on feed intake and satiety in water and was hungry. 32 male Ross broiler chicks reared in groups of four weeks, 16 samples (control and test) were then injected with 0.5 ml chlorpheniramine (40 mg per kg of body weight) intraperitoneally, feed intake and water per chick at intervals of 15, 30, 45, 60, 90 min and2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 21, 23 h after injection and the controls weight was recorded. The results showed that chlorpheniramine in satiety after injection caused a significant decrease (p <0.0001) in feed intake compared with the control group. Chlorpheniramine injection in starvation mode after injection induced a significant decrease (p <0.0001) in feed intake compared with the control group. Satiety in a state of chlorpheniramine in180, 240,300, 360, 420, 480, 540, 600, 660, 720 min after injection (p <0.0001) caused a significant reduction in water use. Chlorpheniramine injection, at 180, 240, 300, 360, 420, 480, 540, 600min after injection (p <0.05) caused a significant reduction in water consumption.
Authors and Affiliations
Zahra Shamsi Biranvand| Department of Animal Science, Ilam University, Ilam, Iran, Seyyed Gholam Reza Mousavi| Department of Animal Science, Ilam University, Ilam, Iran, Mohammad Shamsollahi| Department of Animal Science, Faculty of Agriculture, Islamic Azad University, Ilam Branch, Ilam, IranŮ Corresponding author: shamsollahim@yahoo.com, Javad Cheraghi| Faculty of Para Veterinary Medicine, Ilam University, Ilam, Iran, kamran taherpour| Department of Animal Science, Ilam University, Ilam, Iran
Keywords
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