Effects of different mode high-intensity movement training on articular cartilage in histology - a randomised controlled trial on rabbit knee
Journal Title: Biology of Sport - Year 2008, Vol 25, Issue 4
Abstract
Objective: To study the “starting mechanism” and pathological process of knee cartilage injury in different movement training with high intensity. Materials and Methods: 72 New Zealand white rabbits were divided into 3 groups randomly: Untreated Control Group (CTRL, n=8), animals were untreated by any intervention processing; Running Training Group (RG, n=32), animals were trained running in a treadmill daily; Jumping Training Group (JG, n=32), animals were trained jumping in an electric stimulation cage daily. Rabbits in RT and JT were euthanized at 4 week and 8 week respectively, and knee joints were taken out to be examined histologically. GAG content, thickness of cartilage and subchondral bone, dead cell ratio and Mankin grades were measured respectively. Results: By microexaminations, different pathological changes of early sport injury of knee cartilage in RG and JG were found. Animals receiving jumping training displayed a significantly higher degree of grossly and cartilage matrix detectable degeneration on the weight-loading region of the femur condyles than did animals receiving running training; on the contrary, animals receiving running training displayed a significantly higher degree of chondrocyte damage than did animals receiving jumping training in the earlier stage (4-week). Conclusions: Repetitive and high-intensity jumping exercise can do more harm to cartilage matrix than to chondrocyte in knee joint, the pathogenesis displays as “cartilage matrix starting mechanism”; on the contrary, running exercise can do more harm to chondrocyte than to cartilage matrix, the pathogenesis displays as “chondrocyte starting mechanism”. In addition, the difference in pathogenesis and cartilage damage phenotype by different exercises may have a close correlation with the different loading rate of stress on knee cartilage surface.
Authors and Affiliations
Ch Qi, H Changlin
Keywords
Related Articles
- EP ID EP58953
- DOI -
- Views 159
- Downloads 0
Blood lactate removal using combined massage and active recovery
The effect of combined massage and active recovery on blood lactate removal following a 30-s Wingate anaerobic cycling test (WAnT) was investigated. Maximum oxygen uptake (‡O2max) was estimated for 25 healthy subjects us...
Genome-wide association study identifies three novel genetic markers associated with elite endurance performance
To investigate the association between multiple single-nucleotide polymorphisms (SNPs), aerobic performance and elite endurance athlete status in Russians. By using GWAS approach, we examined the association between 1,14...
GENE DOPING IN SPORT – PERSPECTIVES AND RISKS
In the past few years considerable progress regarding the knowledge of the human genome map has been achieved. As a result, attempts to use gene therapy in patients’ management are more and more often undertaken. The aim...
SPORT EXERCISE CAPACITY OF SOCCER PLAYERS AT DIFFERENT LEVELS OF PERFORMANCE
The aim of the study is to compare the level of exercise capacities to the loads occurring at the lactate threshold among soccer players representing different levels of sport mastery. The research included 51 soccer pla...
Long-term effects of graduated compression stockings on cardiorespiratory performance
The use of graduated compression stockings (GCS) in sport has been increasing in the last years due to their potential positive effects for athletes. However, there is little evidence to support whether these types of ga...