EFFECTS OF ETHANOL DURING GIARDIASIS IN SHEEP INTESTINE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 1
Abstract
Infections with Giardia lamblia are one of the most common intestinal maladies in the world. These infections can lead to acute diarrhea, cramps, and nausea, although asymptomatic infections are the most common. Although most infections are controlled by an effective immune response, some individuals develop chronic disease. The effects of Giardia lamblia infection on D-glucose uptake and brush border enzymes was studied in ethanol fed sheep. Giardia lamblia trophozoite counts were significantly lower in the intestine of ethanol fed sheep than in the controls. Also sodium dependant uptake of D-glucose and brush border enzymes was significantly reduced in the Giardia lamblia infected sheep intestine. There was no change in sodium dependent D-glucose transporter (SGLT-1) and brush border lactase was reduced in Giardia lamblia infected sheep compared with those of controls. However, the mRNA levels encoding these proteins in ethanol fed animals and control animals were in the sheep intestine. The D-glucose malabsorption was observed and probably it causes a significant decrease in activity of disaccharidases in Giardia lamblia infection.
Authors and Affiliations
Ahmed Khan
Keywords
Related Articles
- EP ID EP119545
- DOI -
- Views 116
- Downloads 0
ASSESSMENT OF THE ACCEPTABILITY OF CONTRACEPTIVE USE AMONG THE WOMEN OF RURAL AND URBAN AREAS OF RAWALPINDI, PAKISTAN
Aim of the study was to document the prevalence of use of Contraceptives among the rural and urban areas of Rawalpindi, Pakistan. Specific objectives were to identify the percentage of women using contraceptive, to docum...
REVIEW ON NIOSOMES AS NOVEL DRUG DELIVERY SYSTEM
Niosomes are lamellar structures that are microscopic in size. They constitute of non-ionic surfactant of the alkyl or dialkyl polyglycerol ether class and cholesterol with subsequent hydration in aqueous media. Niosomes...
COMPARATIVEANTIMICROBIAL ACTIVITIESOF NEEM AND CURRY LEAFEXTRACTS AND THEIR SYNERGISTIC EFFECT AGAINST SELECTED PATHOGENIC BACTERIA AND FUNGUS
There is a growing demand today for naturally derived drugs and medicine in place of synthetic drugs that are more commercially available. Such drugs derived from indigenous plants are effective as they contain potent th...
FERMENTATION, MEDIA OPTIMIZATION STUDIES FOR COENZYME Q10 PRODUCTION BY Saccharomyces cerevisiae
To establish the fermentation process for CoQ10 production by using Saccharomyces cerevisiae with subsequent bioprocess media optimization studies. Coenzyme Q10 (CoQ10) is a vitamin-like nutrient that plays a vital role...
FORMULATION AND EVALUATION OF SUSTAINED RELEASE PELLETS OF TRAMADOL HYDROCHLORIDE
The aim of the present research is to develop and evaluate a better sustained release multiple unit pellets (MUP) formulation of Tramadol hydrochloride. Dissolution and diffusion controlled systems have classically been...