EFFECTS OF FOCUSED ULTRASOUND ABLATION ON UTERINE FIBROIDS
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2018, Vol 4, Issue 5
Abstract
Objective: To determine the correlation between magnetic resonance imaging (MRI) features of uterine fibroids (UFs) and therapeutic effects of high-intensity focused ultrasound ablation (HIFUA), and to provide evidence for UFs diagnosis with MRI in clinical practice. Methods: Forty-three UFs patients who were treated in our hospital from April 2015 to June 2017 were selected, including 72 UFs (48 multiple and 24 single UFs). Transverse, sagittal and coronal MRI scanning was performed one week before and after HIFUA to record UF number, location, type (intramural fibroid, submucosal fibroid and subserosal fibroid), mean diameter, hemoperfusion state volume and ablation rate. The patients were followed up in the postoperative 1st, 2nd and 3rd months. Results: HIFUA exerted the best ablative effect on fibroids on the anterior uterine wall (F=26.763, P=0.036). Various types of fibroids were ablated significantly differently (F=3.406, P<0.05) by HIFUA that was most effective for ablating the subserosal ones. Having significantly different ablative effects on UFs with different radial line lengths (F=29.94, P<0.05), HIFUA ablated those with radial line lengths of 3-5 cm most effectively. For UFs with different T2WI signal intensities, HIFUA also functioned significantly differently (F=3.179, P=0. 03). Conclusion: HIFUA exerted significantly different ablative effects on UFs with various MRI features. Therefore, these features were well correlated with the therapeutic effects of HIFUA, allowing MRI as a promising diagnostic protocol.
Authors and Affiliations
Dr. Zille Huma
Keywords
Related Articles
- EP ID EP662813
- DOI -
- Views 136
- Downloads 0
KAP STUDY REGARDING WEANING IN MOTHERS AT A TERTIARY CARE UNIT
Background: Many children in rural communities of developing countries die of malnutrition due to lack of knowledge, resources and certain misconceptions about weaning in mothers which result in low quality weaning foods...
APPLIED ASPECT OF AMAVATA CHIKITSA SUTRA
Context: In ayurveda, most of the diseases are named taking into consideration either the vitiated dosha, dushya, avayava, marga, lakshan and karma. In the same way amavata has been named, taking into account two predomi...
THE PATTERN OF ELECTROPHYSIOLOGICAL ABNORMALITIES IN A GROUP OF ROMANIAN PATIENTS
Introduction: Electrodiagnostic studies measure muscle response or electrical activity in response to nerves stimulation of the muscle and consist in nerve conduction studies, needle electromyography, repetitive stimulat...
NEUTROPHIL LYMPHOCYTE RATIO (NLR): A WELL ASSESSMENT TOOL OF GLYCEMIC CONTROL IN TYPE-2 DIABETIC PATIENTS
Background and Objective: Increased neutrophil lymphocyte ratio (NLR) is a marker as well as predictor of various cardiac and non-cardiac disorders. Our aim was to assess the relationship between NLR and different level...
EVALUATION OF ANTIHYPERLIPIDEMIC AND ANTIDIABETIC ACTIVITY OF HYDRO-ALCOHOLIC EXTRACTS OF MORINGA OLIEFERA SEEDS IN HIGH FAT DIET INDUCED RAT MODEL
The aim of this study was to investigate the Antihyperglycemic and antihyperlipidemic activities of aqueous and ethanol extracts of seeds of Moringa oliefera in alloxan (ALX) induced diabetic rats. Diabetes was confirmed...