Effects Of Generalized Anxiety Disorder On Heart Rate Variability
Journal Title: International Journal of Basic and Applied Physiology - Year 2013, Vol 2, Issue 1
Abstract
Background: Heart rate variability (HRV) is an easy, non-invasive, accurate and reliable tool in assessing autonomic function. Aim: Aim of this study was to determine whether the patients with generalised anxiety disorder have lower heart rate variability compared to healthy controls or not. Objective: To determine and compare heart rate variability in generalized anxiety disorder patients and in age and sex matched healthy controls. Method: Study had been done in 2 groups: 1st group comprises adult patients of generalized anxiety disorder (n=50) & the 2nd group of healthy controls (n=50). It was carried out on instrument windows based Heart rate variability analysis system Variowin-HR at Govt. Medical College, Bhavnagar. Heart-rate variability was studied using the standard protocol and was statistically analyzed. Result: Significantly reduced variability of the heart rate was observed in both the time domain parameters like SDNN (Standard deviation of all NN interval), RMSSD (The square root of the mean of the sum of the squares of differences between adjacent NN intervals), SDSD (Standard deviation of differences between adjacent NN intervals), NN50count (Number of pairs of adjacent NN intervals differing by more than 50 ms in the entire recording), pNN50 (NN50 count divided by the total number of all NN intervals) as well as frequency domain parameters like LF( low frequency), HF (high frequency),LF/HF ratio in the disorder group as compared to the control group which are statistically significant (p<0.05). Conclusion: According to this study, generalized anxiety disorder (GAD) is associated with significantly lower Heart Rate Variability (HRV).
Authors and Affiliations
pravin Rabari, Manjula Jamaliya, Hemant Mehta, Ashok U. Vala, Gunvant Zinzala
Keywords
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