Effects of Hypocaloric Versus Normocaloric Nutrition on Renal Functions and Outcomes in Intensive Care Unit Patients
Journal Title: Turkish Journal of Intensive Care - Year 2021, Vol 19, Issue 1
Abstract
Objective: Current data in intensive care unit (ICU) suggest that at least 70-100% of patients’ energy have to met, while the effects of hypocaloric nutrition (HN) on patient outcomes are questioned. This study aimed to determine the relationship between renal replacement requirement and other organ failure and patient outcomes in normocaloric and hypocaloric fed patients. Materials and Methods: The data of patients followed up in the intensive care unit between 2003-2012 were retrospectively evaluated. Normocaloric nutrition (NN) group is determined as patients with 70%-110% of the daily energy requirement was reached, HN group is determined as patients with less than 70% of their daily energy requirement. Patient data were recorded for 14 days. Results: Data of 1,955 patients were evaluated and 92 patients were included to NN group, 199 patients were included to HN group. There was a significant decrease in Sequential Organ Failure Assessment score in the HN group compared to the hospitalization day (p<0.005). Renal replacement therapy was needed in 19 (20.7%) patients in the NN group, whereas renal replacement was performed in 35 (17.6%) patients in the HN group (p=0.643). In the HN group, the number of RIFLE stage-3 days was 460 (25%), and in the NN group it was 157 (15.1%) days (p<0.001). The length of stay in ICU was 16.88±10.88 days in NN group and 11.42±9.11 days in the HN group (p<0.001). There was no significant difference in ICU mortality and 28th day mortality in both groups (p>0.05). Conclusion: There was no difference between NN and HN in critically ill patients in ICU. Although the duration of ICU stay was less in the hypocaloric group, no significant difference was found between low-calorie intake and 28th day and hospital mortality. There is still a need for a prospective, randomized controlled trial on this subject.
Authors and Affiliations
Ahmet Oğuzhan Küçük, Mehtap Pehlivanlar Küçük, Hülya Ulusoy
Keywords
Related Articles
- EP ID EP693478
- DOI 10.4274/tybd.galenos.2020.15045
- Views 94
- Downloads 0
Effective Lipid Emulsion Treatment of a Venlafaxine Intoxication Case with Status Epilepticus
Venlafaxine is a serotonergic and noradrenergic antidepressant. It shares serotonergic adverse effects with selective serotonin reuptake inhibitor (SSRI) antidepressants and causes noradrenergic adverse effects in partic...
Renal Resistive Index is Unsusceptible to Systemic Hemodynamics in Fluid Responsive Critically Ill Patients
Objective: The primary goal of fluid resuscitation in critically ill patients is to improve oxygen delivery to ensure adequate organ perfusion. Little evidence is known about renal response to fluids in the acute phase,...
Effects of Hypocaloric Versus Normocaloric Nutrition on Renal Functions and Outcomes in Intensive Care Unit Patients
Objective: Current data in intensive care unit (ICU) suggest that at least 70-100% of patients’ energy have to met, while the effects of hypocaloric nutrition (HN) on patient outcomes are questioned. This study aimed to...
The Toxic Effects of Lithium Combined with Quetiapine and Risperidoneon Organ Systems
Lithium, first approved by the American Food and Drug Administration (FDA) for mania treatment in 1970, is used as the gold standard in the treatment of bipolar disorder in these days. Its neuroprotective effects, its us...
Predicting Factors Affecting Post-operative Flap Complications in Patients Undergoing Flap Reconstruction Due to Tissue Defect in Lower Extremity
Objective: To evaluate the predicting factors affecting post-operative free flap complications in patients who underwent flap reconstruction due to tissue defect in the lower extremity and who were followed up in the int...