Effects of Intravenous Dexmedetomidine On 5% Hyperbaric Lidocaine (Xylocaine) Spinal Anaesthesia -A Placebo Controlled Randomized Controlled Trial
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
The objective of the study was to evaluate the effect of intravenous dexmedetomidine on the duration of subarachnoid block and sedation in patients undergoing surgeries under spinalanaesthesia with 5% lidocaie. 80 ASA physical status I/II patients undergoing elective surgeries under spinal anaesthesia were randomized into two groups of 40 each. Immediately after subarachnoid block with 2 ml of 5% hyperbaric lidocaine, group D patients received a loading dose of 1 μg/kg of dexmedetomidine intravenously by infusion pump over 10 mins followed by a maintenance dose of 0.5 μg/kg/hr till the end of surgery whereas group C received an equivalent quantity of normal saline by infusion pump. Time taken for regression to Modified Bromage Scale 0, level of sensory block, two dermatomal regression of sensory blockade, duration of sensory block and intraoperative Ramsay sedation scores were higher in group D compared to group C (p values < 0.001). In conclusion, intravenous dexmedetomidine significantly prolongs the duration of sensory and motor block of lidocaine spinal anaesthesia with good hemodynamic stability.
Authors and Affiliations
Dr. K. Uma Manjula, Dr. D. Sangeetha Rao
Keywords
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- EP ID EP375892
- DOI 10.9790/0853-1706042229.
- Views 59
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