EFFECTS OF LONG-TERM CONSUMPTION OF INDOMIE NOODLES ON THE BODY AND BRAIN WEIGHTS OF ADULT WISTAR RATS
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2017, Vol 6, Issue 12
Abstract
Background of Study: The effect of long-term consumption of indomie noodles the body and brain weights of adult Wistar rats was carefully studied. Method: Twenty four adult Wistar rats, with average weight of 200g were randomly assigned into three groups (A,B,C): Two treatments (n1+ n2=16) and control (n3=8) groups. The rats in the treatment group A received cooked un-seasoned indomie noodles, those in B received cooked seasoned indomie noodles while rats in group C (control) received normal rat feeds for thirty days. All animals were given distilled water liberally throughout the period of the experiment. The weight of the rats were measured daily during the period of the study. The rats were sacrificed by cervical dislocation on the thirty-first day of the experiment and their brains were carefully dissected out, weighed using Mettler Toledo weighing balance. The weight obtained from the control and treatments groups were recorded and compared statistically using the unpaired sample T-test and symmetric measured test of the Statistical Package for Social Sciences (SPSS). Results: The results of this experiment revealed significant (p < 0.05) increases in body weights and significant decrease (p < 0.05) in brain weights (g) and relative brain weights (%) of the animals treated with instant noodles as compared to their corresponding control animals. Conclusion: Long-term consumption of indomie noodles could therefore have adverse effects on the body and brain weights of adult Wistar rats.
Authors and Affiliations
Kingsley Afoke Iteire
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