Effects of lycopene on the skeletal system
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2015, Vol 69, Issue 0
Abstract
Antioxidant substances of plant origin, such as lycopene, may favorably affect the skeletal system. Lycopene is a carotenoid pigment, responsible for characteristic red color of tomatoes. It is believed that lycopene may play a role in the prevention of various diseases; despite theoretical premises and results of experimental studies, the effectiveness of lycopene has not yet been clearly demonstrated in studies carried out in humans. The aim of the study was to present the current state of knowledge on the effects of lycopene on the osseous tissue in in vitro and in vivo experimental models and on the skeletal system in humans.Results of the studies indicate that lycopene may inhibit bone resorption. Favorable effects of high doses of lycopene on the rat skeletal system in experimental conditions, including the model of osteoporosis induced by estrogen deficiency, have been demonstrated. The few epidemiological and clinical studies, although not fully conclusive, suggest a possible beneficial effect of lycopene present in the diet on the skeletal system.
Authors and Affiliations
Patrycja Sołtysiak, Joanna Folwarczna
Rola probiotyków w zapobieganiu chorobom jamy ustnej
Dynamiczny rozwój wiedzy na temat probiotyków rozpoczął się na początku XX w. Od tego czasu opracowano wiele sposobów ich wykorzystania w medycynie. Probiotyki zgodnie z definicją WHO „są żywymi mikroorganizmami, które p...
Tumor blood vessels
Growth of tumors usually depends on the development of the tumor’s own vasculature. Small avascular tumors (1–2 mm3) cannot continue growth provided an equilibrium between pro-angiogenic and anti-angiogenic factors is...
Przerzutowanie w raku piersi – analiza wybranych mechanizmów molekularnych zjawiska
When defense becomes dangerous – transcription factor Nrf2 and cancer
The transcription factor Nrf2 controls the expression of genes encoding cytoprotective enzymes and proteins. Its activation is related to conformational changes in the inhibitory protein Keap1 and/or Nrf2 phosphorylation...
KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression
On the basis of scientific literature, there is growing evidence that KIM-1 and NGAL are interesting and promising biomarkers not only in acute and chronic inflammatory processes but also in oncogenesis. There are a numb...