EFFECTS OF NATURAL PRODUCTS ON BODY WEIGHT AND BIOCHEMICAL PARAMETERS IN HEALTHY RATS
Journal Title: Era's Journal of Medical Research - Year 2017, Vol 4, Issue 2
Abstract
The present study was undertaken to evaluate effect of natural products i.e. Anthocephalus indicus; KADAM, roots, Hibiscus rosa sinensis roots, Tinospora cordifolia stem and Cassia tora seeds in normal healthy rats. In this study ethanol extract of above mentioned medicinal plants had macerated with aqueous gum acacia (2%, w/v) suspension and fed orally (500 mg/kg bw p.o.) to male adult healthy normal rats of Charles Foster strain for 30 days. Results of this study showing that alcoholic extracts caused no any significant reduction in blood glucose, total cholesterol, triglyceride, phospholipids, free fatty acid, lipid peroxide and no significant increased in post heparin lipolytic activity, but on the other hand as per pre-existing data and my published studies in diabetic patients and diabetic experimental animals showed that extracts exerting all above effects significantly. That's why it is very clear here if healthy person will take natural products, it never cause hypoglycemia, hypolipidemia and under weight. Natural products also not cause any significant change on hepato-specific parameters. Thus from this study we conclude that, natural products are safe, non toxic and free from side effects, in comparison to synthetic drugs.
Authors and Affiliations
Vishnu Kumar, Farzana Mahdi, Jitendra Kumar Saxena, Raj Kumar Singh, Mrinal Ranjan Srivastava, Sharique Ahmad
Keywords
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- EP ID EP283030
- DOI 10.24041/ejmr2017.45
- Views 156
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