Effects of non-drug treatment on the parameters of carbohydrate metabolism in patients with non-alcoholic fatty liver disease and obesity
Journal Title: Сучасна гастроентерологія - Year 2018, Vol 0, Issue 3
Abstract
Objective — to determine the efficacy of the complex non-drug treatment (NDT) on the course of non-alcoholic fatty liver disease (NAFLD) in patients with the concomitant obesity and on the associated disorders of the carbohydrate metabolism, in particular insulin resistance. Materials and methods. The investigation involved 105 NAFLD patients (55 men and 50 women, the mean aged 45.0 [37.0; 52.5] years). Patients were randomized in the groups of active NDT: 27 NAFLD patients (group ІB) and 27 NAFLD patients with concomitant obesity (group ІIB), and comparison groups: 25 NAFLD patients (group ІА) и 26 NAFLD patients with concomitant obesity (group ІІА). Results. It has been established that independently from obesity, active NDT associated with the reduction of fasting glycemia (р < 0.05), insulin levels (р < 0.05) and insulin resistance index НОМА (р < 0.05). Conclusions. Active non-drug NAFLD treatment during 24 week promoted the positive dynamics of the disease clinical course, and improvement of associated carbohydrate metabolism disorders.
Authors and Affiliations
O. G. Kurinna, I. E. Kushnir, V. M. Chernova, N. I. Cherelyuk
Keywords
Related Articles
- EP ID EP298615
- DOI 10.30978/MG-2018-3-42
- Views 105
- Downloads 0
Idiopathic non-cirrhotic portal hypertension and Budd — Chiari syndrome: focus on the problem
The idiopathic non-cytolytic portal hypertension and Budd — Chiari syndrome refer to orphan diseases, however last time the incidence of these liver diseases is being increased recently, especially among young people. Th...
Investigation of the effects of the blood plasma levels of C16 ceramides on the course of non-alcoholic fatty liver disease
Objective — to investigate the dependence of the blood plasma levels of C16 ceramides on the degree of liver steatosis in patients with nonalcoholic fatty liver disease (NAFLD) based on the results of steatomometry in co...
Priorities of the diagnostic search for osteopenic conditions in patients with chronic pancreatitis and hypertensive disease
Objective — to study of the relationship between lactase gene polymorphism (LCT C-13910T) and the determination of the state of biochemical markers of bone metabolism (total and ionized serum calcium, osteocalcin) in the...
Role of biochemical and hemodynamic indicators in assessing the progression of liver fibrosis of various origins
Objective — to determine the peculiarities of biochemical and hemodynamic indices in patients with chronic HCV and NAFLD, their interrelations with the liver elastography data. Materials and methods. 195 patients, among...
The features of vegetative and emotional disorders at chronization of duodenal ulcer
Traditionally, duodenal ulcer is referred to the psychosomatic disorders. Not by accident, in the classic investigations of the founder of the stress theory, Canadian scientist R. Selye, acute gastric ulcer serves as a m...