Effects of Propofol and Midazolam on Newborns’ Apgar Scores and Mothers’ Hemodynamic under Spinal Anesthesia
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 5, Issue 5
Abstract
At present, cesarean section is the most prevalent surgical procedure in women and the anesthesia performed for it has turned into a selective technique. This study compared the effects of midazolam and propofol on newborns’ Apgar scores and on the hemodynamic status of the mothers undergoing cesarean sections. This research, in the form of a double-blind clinical trial, was carried out on forty-two15 - 35 year-old of class ASAI and II pregnant women who underwent cesarean section. Using the simple random method, they were divided into two groups of equal members: 21 in the Propofol and 21 in the midazolam groups. The newborns’ Apgar scores were recorded 1 and 5 minutes after birth and the mothers’ hemodynamic status 3, 5, 10, 15, 30, 60 minutes into the surgical procedure. The data was analyzed using SPSS, the repeated measurement test, and the independent t-test. One and five minutes after birth, there were no significant differences between the newborns’ Apgar scores in the two groups (p=0.08), or between the two groups (p=0.33). Results showed there were no statistically significant differences between the Apgar scores of the newborns at low doses of midazolam and propofol.
Authors and Affiliations
Navid Kalani| Medical Ethic Research Center, Jahrom University of Medical Sciences, Jahrom, Iran, Mohammad Sadegh Sanei| Medical Ethic Research Center, Jahrom University of Medical Sciences, Jahrom, Iran, Department of Anaesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran, Hossein Kargar Jahromi| Research center for non.Communicable Diseases , Jahrom University of Medical Sciences, Jahrom, Iran, Hasan Zabetian| Medical Ethic Research Center, Jahrom University of Medical Sciences, Jahrom, Iran, Department of Anaesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran, Correspondence Email:dr_hzabetyan@ymail.com, Mansour Deylami| Department of Anaesthesiology, Golestan University of Medical Sciences, Golestan, Iran
Keywords
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